BACKGROUND A stepped care strategy (SCS) to improve adequate healthcare use in patients with osteoarthritis was developed and implemented in a primary care region in the Netherlands. AIM To assess the association between care that is in line with the SCS recommendations and health outcomes. DESIGN AND SETTING Data were used from a 2-year observational study of 313 patients who had consulted...

Background We developed the stepped care strategy (SCS) to improve adequate health care use in patients with osteoarthritis (OA) and implemented it in a primary care region in the Netherlands. Aim To assess the association between care that is in line with the SCS-recommendations and health outcomes. Design and setting We used data from the 2-year observational study with 313 patients who had c...

objective(s): predegeneration is a standard technique to obtain mitotically activated and enriched cultures of schwann cells (scs). this study, for the first time, evaluated the impact of various duration of predegeneration on cell yield and enrichment of scs from dog peripheral nerve. materials and methods: dog sural nerves were subjected to 5, 10, 15 day-long in vitro predegeneration. the tot...

Introduction: Transplantation of bone marrow stromal cells (BMSCs) or Schwann cells (SCs) can increase axonal regeneration in peripheral nerve injuries. Based on our previous investigations, the goal of the present work was to examine the individual and synergistic effects of the two different cell types in sciatic nerve injury . We pursued to evaluate the effects of BMSCs and SCs co-transplant...

BACKGROUND The use of the Self-Compassion Scale (SCS) as a single measure has been pointed out as problematic by many authors and its originally proposed structure has repeatedly been called into question. The negative facets of this construct are more strongly related to psychopathology than the positive indicators. The aim of this study was to evaluate and compare the different structures pro...

objective: transplantation of bone marrow stromal cells (bmscs) or schwann cells (scs) can facilitate axonal regeneration in peripheral nerve injuries. the aim of this study was to compare the effects of transplantation of bmscs and scs on functional recovery after injury to the sciatic nerve in the rat. materials and methods:in this experimental research, adult male wistar rats (n=24, 250-300 ...

BACKGROUND Several mechanisms were suggested in the past to explain the beneficial effect of spinal cord stimulation (SCS) in patients suffering from neuropathic pain. Little is known about potential supraspinal mechanisms. OBJECTIVE In this study cortical signaling of patients with neuropathic pain and successful long-term treatment with SCS was analyzed. STUDY DESIGN Observational study. ...