Radiation-associated colon cancer is a rare clinical entity. We herein describe the case of a patient with radiation-associated colon cancer who had undergone low anterior resection for rectal cancer following preoperative radiotherapy. Certain characteristics of radiation-associated colon cancer are highlighted. The patient was a 48-year-old man who had undergone low anterior resection for rec...

esophageal cancer is one of the most common malignancies in our country. patients often seek medical advice in advanced and inoperable stages or with cervical esophageal cancer, in which operation is accompanied by sever morbidity. in this conditions many of them cannot tolerate chemo-radiation, or refuse it. therefore radiotherapy is applied as a single modality in palliation of many patients ...

BACKGROUND For patients with resectable rectal cancer chemoradiation (CRT) or short-course preoperative radiotherapy (SCPRT) reduces locoregional failure, without extending disease-free survival (DFS) or overall survival (OS). Compliance to postoperative adjuvant chemotherapy is poor. Neoadjuvant chemotherapy (NACT) offers an alternative strategy. METHODS A systematic computerised database se...

man rectal cancer trial (CAO/ ARO/AIO-94) now made public, we have a prospective randomized study that has confirmed what those treating rectal cancer have long suspected: preoperative chemoradiation provides a significant advantage over postoperative therapy in terms of pelvic control and sphincter preservation. Full-course radiation therapy with 5-fluorouracil-based chemotherapy, similar to t...

In addition to clinical factors (tumor and node stage) and treatment factors (equivalent radiotherapy dose and chemotherapy regimen), we assessed whether different performances of various tumor volume measurements help predict the pathological complete response (pCR) of locally advanced rectal cancer (LARC) after preoperative concurrent chemoradiotherapy (CCRT). A total of 122 patients with LAR...

Abstract Introduction Neoadjuvant long course chemo-radiotherapy (LCCR) is the standard of care for locally advanced rectal cancer. In June 2013 this institution implemented preoperative MRI post LCCR in an attempt to improve R0 resection rate. The aims projects were audit compliance with new policy and assess whether it had impact on Method All patients who underwent after between February 201...

Introduction: Pituitary Adenomas account for approximately 10-15% of all intracranial tumors. They are classified according to their secretory activity, presenting with varied hormonal and visual symptoms. The aim treatment pituitary adenomas is reversal endocrine dysfunction preservation normal function, along decompression nervous structures control tumor growth in large Aims Objective: this ...

IntroductionThe Neoadjuvant rectal (NAR) score is a new surrogate endpoint to be used in clinical trials for early determination of treatment response different preoperative therapies. The aim further validate the NAR-score, primarily developed using chemoradiotherapy (CRT) with delay surgery 6–8 weeks, and explore its value other schedules.Materials MethodsThe study included all 9978 patients ...

The optimal management of rectal cancer remains a major challenge for oncologists. The treatment of stage II/III rectal cancer has historically been associated with a high risk of local recurrence and poor survival, which led to the development of adjuvant treatments in the hope of improving outcomes. The approach to adjuvant therapy for rectal cancer currently varies widely between Europe and ...