A patient who underwent a successful double-vessel percutaneous transluminal coronary angioplasty (PTCA) had suffered from exercise-induced ST-segment elevation associated with angina pectoris (AP). This ECG pattern was present both before and 12 months after PTCA while nifedipine (Adalat; Bayer-Miles) therapy was electively discontinued. Reintroduction of calcium blockade with this drug elimin...

W hen, approximately two centuries ago, the syndrome of angina pectoris was first described and named, one effect was controversy, which has waxed and waned until the present time. However, from the very first, the clinical syndrome has emphasized pain-pain that was precordial, pain that signaled the onset of the syndrome with exertion, vanishing pain that signaled the offset of the syndrome wi...

To study the vasomotility of normal and diseased coronary arteries during dynamic exercise, symptom-limited supine bicycle exercise during cardiac catheterization was performed by 18 patients with classic angina pectoris. The cardiovascular response was assessed by hemodynamic measurements and computer-assisted determination of normal and stenotic coronary artery luminal areas from biplane coro...

BACKGROUND There is growing evidence for a pathogenic role for cytokines in atherogenesis. The presence of certain cytokines has been documented in human atherosclerotic vessels. This study was designed to investigate cytokine production by mononuclear leukocytes from patients with ischemic heart disease. METHODS AND RESULTS We measured kinetics of secretion of tumor necrosis factor-alpha (TN...

this article describes coronary artery bypass grafting by avlliath jay akrishnan et al. one of the most common reason for coronary artery bypass grafting is narrowing coronary arteries because of atherosclerosis. atherosclerosis causes chest pain (angina pectoris), myocardial infarction and sudden death. the aim of coronary artery bypass grafting is to release pain, prevention of myocardial inf...

Angina pectoris is a clinical manifestation that results from coronary atherosclerotic heart disease. An acute anginal attack (secondary angina) is thought to occur because of an imbalance between myocardial oxygen supply and demand owing to the inability of coronary blood flow to increase in proportion to increases in myocardial oxygen requirements. This is generally the result of severe coron...

The era of randomised studies of coronary artery bypass surgery''-7 has probably come to an end. It is, therefore, opportune to assess the present state of this form of surgery in the light of the information available from these trials. There is general agreement that coronary artery bypass surgery is effective in relieving angina pectoris, but controversy persists as to whether it can improve...

Evaluation of the results of surgery for coronary artery disease requires a knowledge of the clinical course of patients not having this mode of treatment. To obtain such information we performed a retrospective analysis of the fate of 266 patients with arteriographically documented significant stenosis followed from one to ten years. For the entire group the five year survival was 73%. Subdivi...

0 B J E C T IV E S: Our objective was to prospectively evaluate the diagnostic performance of the high-speed dual-source computed tomography scanner (DSCT), with an increased temporal resolution (83 ms), for the detection of significant coronary lesions (2": 50% lumen diameter reduction) in a clinically wide range of patients. BACK G R 0 UN D: Cardiac motion artifacts may decrease coronary imag...