OBJECTIVES To evaluate the characteristics of the cornea in myopic patients. MATERIAL AND METHOD A retrospective study of 420 eyes in 210 patients who visited the Excimer Laser Surgery Clinic at Siriraj Hospital, Mahidol University from January 1999 to June 2002 was conducted. All cases that were eligible for myopic refractive surgery were included in the present study. A preoperative ocular ...

AIMS To evaluate the distribution, morphometry and the postmortem changes of the central and peripheral human corneal nerves by exvivo laser-scanning confocal microscopy (EVCM). METHODS 24 eyes from 14 cadavers were retrieved at different time intervals after death and examined by EVCM. Five regions were examined in each eye: central, superior, inferior, temporal and nasal. In each region, co...

CASE REPORT An 83 year-old male reported to the emergency room with red eye and ocular pain. The slit-lamp examination showed a central corneal perforation of 1mm in diameter, with no associated infection or inflammatory process. The patient had no history of trauma. It was decided to apply a patch of Tachosil(®) at the site of corneal perforation. After 36 hours of occlusion, a layer of fibrin...

PURPOSE To report two cases of femtosecond laser-assisted small incision deep lamellar endothelial keratoplasty (DLEK) for patients with corneal endothelial decompensation by Fuchs dystrophy and glaucoma METHODS Femtosecond laser (IntraLase; IntraLase Corp., Irvine, CA) with 15 kHz of repetition rate, was used for a 9.5 mm diameter by 400 micrometer thickness donor corneal lamellar dissection...

PURPOSE Klf4, one of the highly expressed transcription factors in the mouse cornea, plays an important role in maturation and maintenance of the ocular surface. In this study, the structure and proteoglycan composition of the Klf4 conditional null (Klf4CN) corneal stroma was investigated, to further characterize the previously reported Klf4CN stromal edema. METHODS Collagen fibril spacing an...

PURPOSE To investigate the changes in corneal backward light scattering, as measured by a rotating Scheimpflug camera with automated corneal densitometry software, in eyes treated with femtosecond laser-assisted LASIK (FS-LASIK). METHODS The cornea was examined preoperatively and postoperatively at 1 day, 1 week, and 1, 3, and 6 months in 23 patients who underwent myopic FS-LASIK. Local analy...

PURPOSE To compare the effects of biaxial microincision cataract surgery (B-MICS) and microcoaxial cataract surgery (C-MICS) techniques on corneal optical quality. MATERIALS AND METHODS In this prospective study, 40 eyes underwent B-MICS and 40 eyes C-MICS. Corneal aberrations were derived from conversion of the corneal elevation profile into corneal wavefront data with 6.0  mm aperture diame...

purpose : to investigate the validity of pentacam derived parameters like corneal volume distribution and percentage increase in volume in differentiation of mild to moderate keratoconus from normal corneas methods : forty eyes with mild to moderate keratoconus and 200 normal eyes were studied by pentacam. corneal volume was calculated within diameters from 1.0 to 7.0 mm with 0.5 mm steps cente...