نتایج جستجو برای: core 174

تعداد نتایج: 224565  

Journal: :Archives of biochemistry and biophysics 2004
Cinta Hernández Sebastià Shane C Hardin Steven D Clouse Joseph J Kieber Steven C Huber

1-Amino-cyclopropane-1-carboxylate synthase (ACS) catalyzes the rate-determining step in the biosynthesis of the plant hormone ethylene, and there is evidence for regulation of stability of the protein by reversible protein phosphorylation. The site of phosphorylation of the tomato enzyme, LeACS2, was recently reported to be Ser460, but the requisite protein kinase has not been identified. In t...

2009
Benjamin Dickins Anton Nekrutenko

Experimental evolution in rapidly reproducing viruses offers a robust means to infer substitution trajectories during evolution. But with conventional approaches, this inference is limited by how many individual genotypes can be sampled from the population at a time. Low-frequency changes are difficult to detect, potentially rendering early stages of adaptation unobservable. Here we circumvent ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1970
A Razin R L Sinsheimer

The progeny replicative form II DNA isolated from E. coli cells infected with varphiX174 is resistant to the exonucleolytic activity associated with E. coli DNA polymerase. A limited endonucleolytic cleavage with micrococcal endonuclease renders the replicative form II molecule susceptible to the exonucleolytic activity associated with the E. coli DNA polymerase. These experiments suggest that ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1981
R M Schaaper L A Loeb

Introduction of apurinic sites into phi X174 am3 DNA leads to loss of biological activity when measured in a transfection assay. For single-stranded DNA, approximately one apurinic site constitutes a lethal hit; for double-stranded (RFI) DNA, approximately 3.5 hits per strand are lethal. When the reversion frequency of am3 DNA is measured, no increase due to depurination is observed above the b...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه پیام نور - دانشگاه پیام نور مرکز - دانشکده شیمی 1391

dendrimer synthesis strategies now provide virtual control of macromolecular nanostructures as a function of size and surface/interior functionality. these strategies involve the covalent assembly of hierarchical components reactive monomers , branch cells or dendron’s around atomic or molecular cores according to divergent/convergent dendrite branching principles.combinon of two or more dendri...

Journal: :The New phytologist 2007
Yair Shachar-Hill

Dickie IA. 2007. Host preference, niches and fungal diversity. New Phytologist 174: 230–233. Fitter AH. 2006. What is the link between carbon and phosphorus fluxes in arbuscular mycorrhizas? A null hypothesis for symbiotic function. New Phytologist 172: 3–6. Govindarajulu M, Pfeffer PE, Jin H, Abubaker J, Douds DD, Allen JW, Bücking H, Lammers PJ, Shachar-Hill Y. 2005. Nitrogen transfer in the ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1989
J Schneck T Munitz J E Coligan W L Maloy D H Margulies A Singer

The class I and class II major histocompatibility complex (MHC) antigens are polymorphic cell-surface glycoproteins that present antigenic peptides to T lymphocytes in the generation of immune responses. While much is known about the recognition and processing of antigens, the nature of T-cell recognition sites on MHC molecules is poorly understood. Both structural and functional studies have s...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2014
Wen-Jing Shi Hao Liu Dan Wu Zhen-Hua Tang Yu-Chen Shen Lin Guo

Interleukin-6 (IL-6), a central proinflammatory cytokine, maintains immune homeostasis and also plays important roles in cervical cancer. Therefore, we aimed to evaluate any associations of IL-6 gene polymorphisms at positions -174 and -572 with predisposition to cervical cancer in a Chinese population. The present hospital- based case-control study comprised 518 patients with cervical cancer a...

Journal: :The Biochemical journal 1997
L Bertrand J Deprez D Vertommen A Di Pietro L Hue M H Rider

In a structural model of the 2-kinase domain of the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase based on the analogy with adenylate kinase, Lys-174, Asp-179 and Asp-191 residues are located in the putative active site. Asp-179 and Asp-191 are conserved in all known 6-phosphofructo-2-kinase sequences. In contrast, Lys-174 is conserved except in a yeast isoenzyme, fbp...

2014
Xiang Li Wei Chai Ming Ni Meng Xu Zijian Lian Lewis Shi Yang Bai Yan Wang

BACKGROUND Interleukin-4 (IL-4) and interleukin-6 (IL-6) have been reported to associate with pathogenesis of rheumatoid arthritis (RA); however, the role of IL-4 and IL-6 genetic polymorphisms in RA remains unknown. METHOD A total of 752 unrelated Chinese patients with RA and 798 healthy Chinese volunteers with no family histories of any autoimmune diseases were recruited. The promoter IL-4-...

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