نتایج جستجو برای: copper level

تعداد نتایج: 1158171  

2016
Thomas Sheppard Helen Daly Alex Goguet Jillian M Thompson

The mono(μ-oxo) dicopper cores present in the pores of Cu-ZSM-5 are active for the partial oxidation of methane to methanol. However, copper on the external surface reduces the ratio of active, selective sites to unselective sites. More efficient catalysts are obtained by controlling the copper deposition during synthesis. Herein, the external exchange sites of ZSM-5 samples were passivated by ...

Journal: :Archives of disease in childhood 1973
J Walker-Smith J Blomfield

Walker-Smith, J. A., and Blomfield, J. (1973). Archives of Disease in Childhood, 48, 476. Wilson's disease or chronic copper poisoning? The case history is given of a child who presented at 14 months with ascites and was found to have severe micronodular cirrhosis with biochemical evidence of Wilson's disease, but in view of the severity of the pathology and early age of presentation, the possi...

Journal: :Molecular pharmacology 2008
Im-Sook Song Helen H W Chen Isamu Aiba Anwar Hossain Zheng D Liang Leo W J Klomp Macus Tien Kuo

Copper is an essential metal nutrient, yet copper overload is toxic. Here, we report that human copper transporter (hCtr) 1 plays an important role in the maintenance of copper homeostasis by demonstrating that expression of hCtr1 mRNA was up-regulated under copper-depleted conditions and down-regulated under copper-replete conditions. Overexpression of full-length hCtr1 by transfection with a ...

Journal: :Genes & development 1993
P Zhou D J Thiele

Copper detoxification in the yeast Candida glabrata is carried out in large part by a family of metallothionein (MT) genes: a unique MT-I gene, a tandemly amplified MT-IIa gene, and a single unlinked MT-IIb gene. In response to elevated environmental copper levels, members of this MT gene family are transcriptionally activated by a copper-dependent, sequence-specific DNA-binding transcription f...

Journal: :Nature chemistry 2015
Jing Wang Cheng Luo Changliang Shan Qiancheng You Junyan Lu Shannon Elf Yu Zhou Yi Wen Jan L Vinkenborg Jun Fan Heebum Kang Ruiting Lin Dali Han Yuxin Xie Jason Karpus Shijie Chen Shisheng Ouyang Chihao Luan Naixia Zhang Hong Ding Maarten Merkx Hong Liu Jing Chen Hualiang Jiang Chuan He

Copper is a transition metal that plays critical roles in many life processes. Controlling the cellular concentration and trafficking of copper offers a route to disrupt these processes. Here we report small molecules that inhibit the human copper-trafficking proteins Atox1 and CCS, and so provide a selective approach to disrupt cellular copper transport. The knockdown of Atox1 and CCS or their...

2014
Baba Ngom Yili Liang Xueduan Liu

A cross-comparison of six strains isolated from two different regions, Chambishi copper mine (Zambia, Africa) and Dexing copper mine (China, Asia), was conducted to study the leaching efficiency of low grade copper ores. The strains belong to the three major species often encountered in bioleaching of copper sulfide ores under mesophilic conditions: Acidithiobacillus ferrooxidans, Acidithiobaci...

2006
JOHN WALKER-SMITH JEANETTE BLOMFIELD

Walker-Smith, J. A., and Blomfield, J. (1973). Archives of Disease in Childhood, 48, 476. Wilson's disease or chronic copper poisoning? The case history is given of a child who presented at 14 months with ascites and was found to have severe micronodular cirrhosis with biochemical evidence of Wilson's disease, but in view of the severity of the pathology and early age of presentation, the possi...

2012

Twenty-four male weanling rats were randomly divided into two treatment groups, namely a copper-adequate (8 mg Cu/kg diet) or a copper-deficient (0.85 mg Cu/kg diet) group. Feed and distilled, deionized water were provided ad libitum. After 7 weeks, plasma lipid, protein and apolipoprotein concentrations of high density lipoproteins (HDL) and subfractions of HDL were determined. Significant ele...

Journal: :Journal of clinical neuromuscular disease 2012
Shanna K Patterson Peter H R Green Christina A Tennyson Suzanne K Lewis Thomas H Brannagan

OBJECTIVE Neurological complications of celiac disease (CD) include neuropathy, myeloneuropathy, and cerebellar degeneration. The cause of neuropathy in patients with CD is not known. Prior publications describe copper deficiency in CD patients with myeloneuropathy and neuropathy and posit that hypocupremia is the cause of these neurological conditions. However, based on our clinical experience...

Jafari, Sattar, Mazloomzadeh, Saeideh, Mohseni, Mehran, Rezaei, Saeed,

Back ground: Gastric cancer is an important, prevalant and second most fatal cancer in the world. Previous studies show heavy metals have various roles in human health. Heavy metals are known to be associated with various cancers but their function in gastric adenocarcinoma is unclear. In this study we examined serum level of these metals in gastric adenocarcinoma patients compared to control g...

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