PURPOSE Visual impairment, resulting from ocular abnormalities or brain lesions, can significantly affect driving performance. The impact of vestibulopathy on head-eye coordination is also a concern in vehicle operation safety, yet to date there has been little functional research in this area. An understanding of decrements in driving ability resulting from visual and vestibular pathology, plu...

Mice devoid of glial fibrillary acidic protein (GFAP), an intermediate filament protein specifically expressed in astrocytes, develop normally and do not show any detectable abnormalities in the anatomy of the brain. In the cerebellum, excitatory synaptic transmission from parallel fibers (PFs) or climbing fibers (CFs) to Purkinje cells is unaltered, and these synapses display normal short-term...

Children with developmental dyslexia show reading impairment compared to their peers, despite being matched on IQ, socio-economic background, and educational opportunities. The neurological and cognitive basis of dyslexia remains a highly debated topic. Proponents of the magnocellular theory, which postulates abnormalities in the M-stream of the visual pathway cause developmental dyslexia, clai...

AIM To evaluate the incidence and severity of the impairment of selected cognitive functions in patients after sudden cardiac arrest (SCA) in comparison to patients after myocardial infarction without SCA and healthy subjects and to analyze the influence of sociodemographic and clinical parameters and the duration of cardiac arrest on the presence and severity of the described disorders. MATE...

This study focuses on identification of children with motor coordination problems and investigates whether the incidence of children with such problems in a normal school setting in Norway is comparable to that found in other countries using the same tests and criteria. The study also examines whether there would be any agreement between two motor tests, the Test of Motor Proficiency (TMP) and ...

OBJECTIVE This study sought to validate the use of the Self-Report Assessment of Functional Visual Performance (SRAFVP) as a measure of the severity of activity of daily living (ADL) limitations in people with homonymous hemianopia (HH). METHOD Thirty adults with HH from stroke rated their level of difficulty in completing the SRAFVP. RESULTS The Cronbach's αs of the SRAFVP and its three su...


 Patient navigation programs are generally community-based service delivery interventions (such as collaborative care, coordinated and case management) intended to enhance timely access the diagnosis treatment of individuals with chronic conditions, including dementia.
 Overall, for care compared usual clinical findings were either mixed or there no between-group differences in terms...

Ataxia represents a pathological coordination failure that often involves functional disturbances in cerebellar circuits. Purkinje cells (PCs) characterize the only output neurons of the cerebellar cortex and critically participate in regulating motor coordination. Although different genetic mutations are known that cause ataxia, little is known about the underlying cellular mechanisms. Here we...