Background and Objectives: Hippocampal volume reduction has been reported in diabetes mellitus type 1. It is believed that hyperglycemia and oxidative stress mediate neuropathological changes in hippocampal neurons. In this study we aimed to study the effect of insulin and an antioxidant like ascorbic acid on preventing volume changes of dentate gyrus and CA3 region of hippocampus. Material...

Background: Most research on autonomic dysfunction of diabetes mellitus is conducted on ganglions innervating gastrointestinal (GI) tract and there are limited works focusing on cervical sympathetic ganglia. The effects of diabetes mellitus (DM) on the neurons of superior cervical sympathetic ganglion (SCSG) are investigated by stereological methods. Material and Methods: Female rats (n=72) ran...