PURPOSE To examine the expression of VEGF in extranodal marginal zone B-cell lymphoma (EMZL) and reactive lymphoid hyperplasia (RLH) of human ocular adnexa, and analyze the correlation with the intratumoral microvessel density (MVD). METHODS Twenty-two EMZL and 16 RLH tissues were examined in this study. Paraformaldehyde-fixed, paraffin-embedded tissue sections were processed for immunohistoc...

BACKGROUND Conjunctival myxomas are rare, benign, connective tissue tumours that classically present as slow-growing, painless, well-circumscribed masses (Arch Ophthalmol 124:735-8, 2006; Case Rep Ophthalmol 3:145-50, 2012). There have been 29 cases reported in the literature (Arch Ophthalmol 124:735-8, 2006; Malays J Med Sci 20(1):92-4, 2013; Case Rep Ophthalmol 3:145-50, 2012; Middle East Afr...

background: normal bacterial flora of the conjunctiva, which inhibits growth of opportunistic organisms, has an important role in the prevention of ocular infections. if resident flora is inhibited by disease or long-term application of antibiotics, opportunistic pathogens overgrow, leading to disease. objectives: the aim of this study was to investigate the effects of ophthalmic chloramphenico...

PURPOSE To examine the novel application of a commercially available optical coherence tomography (OCT) system toward molecular histopathology using gold nanorod (GNR) linked antibodies as a functionalized contrast agent to evaluate ocular surface squamous neoplasia (OSSN). METHODS GNRs were synthesized and covalently attached to anti-glucose transporter-1 (GLUT-1) antibodies via carbodiimide...

Summary An 11‐year‐old crossbreed mare was presented with a nodular, pink mass at the temporal corneolimbal junction of right eye. Histopathology confirmed diagnosis invasive squamous cell carcinoma. The underwent lamellar keratectomy and conjunctivectomy under general anaesthesia, followed by adjunctive topical chemotherapy 1% 5‐fluorouracil solution for 10 days post‐operatively. Adverse effec...

A technique (based on Gipson and Grill, Invest Ophthalmol Vis Sci 23:269, 1982) has been developed to obtain pure, viable, intact sheets of rabbit conjunctival epithelium free of the underlying basement membrane. After preparing a full thickness eye wall resection, Dispase, grade II (neutral protease-Bacillus polymyxa), 1.2 Units/ml MEM is injected intrasclerally. The conjunctiva and sclera are...

BACKGROUND Sarcoidosis is an idiopathic, multi-system, granulomatous disease with well-described ocular manifestations. However, other uveitic etiologies can manifest in a similar fashion, and ocular disease may precede systemic manifestations. Definitive diagnosis requires histologic confirmation of non-caseating granulomatous inflammation. This study reports the diagnostic yield of directed b...

BACKGROUND To evaluate whether tumour-associated lymphangiogenesis, that is the formation of new lymphatic vessels (LVs) induced by a tumour, occurs in and around conjunctival malignant melanoma (MM). METHODS Clinical files and conjunctival specimens of 20 patients with histologically diagnosed conjunctival MM were analysed. Sections were stained with LYVE-1 and podoplanin antibodies as speci...