Congenital (CN) and latent/manifest latent nystagmus (LMLN) are the two most common types of benign infantile nystagmus. They can be distinguished definiti�ely by eye-movement recordings; their clinical characteristics are too similar to allow reliable differential diagnosis. Most treatments for CN, surgical or optical, depend on exploitation of either a gaze-angle or convergence null. Other tr...

PURPOSE We wished to determine the effectiveness of horizontal rectus tenotomy in changing the nystagmus of children with infantile nystagmus syndrome. DESIGN This was a prospective, noncomparative, interventional case series in five children with varied sensory and oculographic subtypes of congenital nystagmus (including asymmetric (a)periodic alternating nystagmus) and no nystagmus treatmen...

Patients with congenital types of nystagmus, including congenital nystagmus (CN), latent/manifest latent nystagmus (LMLN) and combinations of the two, can be identified by waveform analysis and classified into three unambiguous groups. This categorization by waveform is supported by different clinical signs, including the relationship to strabismus. Strabismus is essential for LMLN but incident...

PURPOSE To determine a gene locus for a family with a dominantly inherited vestibulocerebellar disorder characterised by early onset, but not congenital nystagmus. DESIGN Observational and experimental study. METHODS We carried out a phenotypic study of a unique four generation family with nystagmus. We performed genetic linkage studies including a genome wide search. RESULTS Affected fam...

PURPOSE To determine the effect of horizontal rectus muscle surgery on visual acuity, head posture and electronystagmographic indices in patients with congenital nystagmus. METHODS This prospective comparative case series was conducted on 58 patients with congenital nystagmus over a period of three years. Patients were divided into three groups: the first group (29 cases) had head posture les...

Our objective was to translate the past 40 years of infantile nystagmus syndrome (INS) research (i.e., ocular motor recording and control-systems analysis) into a therapeutic approach. Our eye movement recordings use infrared reflection, mag­ netic search coil, and high-speed digital video sys­ tems. Each eye was calibrated during monocular fixation (fellow-eye occluded). We analyzed and displa...