Chylothorax due to goiter is an exceptional compressive complication; compressive goiter usually causes narrowing of the trachea and compression of the esophagus or jugular vein. Because of anatomical relationship, right-side chylothorax is caused by a very large and low-lying goiter. In those cases usually the surgical approach is a sternotomy instead of transcervical thyroidectomy, that is as...

Upper tracheal obstruction, stridor and dispnea developed in a 53 year-old woman because of a large calcified benign goiter. There was a mass of 3 to 4 cm in size with calcification located on the right side of trachea and in the substernal region on the chest roentgenography. CT revealed bilaterally nodular substernal goiter and tracheal compression with the calcified nodule. Cytological findi...

We report an unusual case in which a patient presented with a large posterior mediastinal goiter that extended to the level of the aorta. The goiter was resected through a standard Kocher neck incision with mediastinoscopic assistance. The large goiter was completely excised without the need for a sternotomy.

Intrathoracic goiter is commonly located in the anterior mediastinum. Here we report a case of a 58-year-old Chinese male in whom we successfully removed the intrathoracic goiter and eased his dyspnea by a right posterolateral thoracotomy approach. Posterior mediastinal thyroid goiter with mediastinal compressive symptoms is an indication of surgery.

goiter is common among growing children and adolescents but thyrotoxicosis is a rare thyroid disorder in this age prevalence of thyrotoxicosis and clinical presentation in prevalence of thyrotoxicosis and clinical presentation of the disease among children and adolescents of the disease among children and adolescents presenting for goiter at the clinics of pediatric presenting for goiter at the...

OBJECTIVE MR imaging and sonography are considered to be among the most reliable methods available for estimating goiter volume. Our aim was to assess the observer variability of MR imaging for estimating the volume of a large multinodular goiter and the dimensions of the related trachea. Additionally, we compared the goiter volume estimates from MR imaging with those from sonography. SUBJECT...

Hashimoto's thyroiditis (HT) is usually considered to be manageable by levothyroxine (L-T4) administration, which can reduce the thyroid volume and supplement the lack of hormone. However, we sometimes encounter a huge goiter that has not shrunk in response to L-T4 therapy. These goiters continue to produce symptoms of compression and an unsightly appearance. Here we discuss the surgical indica...

The use of thyroid-depressant agents in the control of hyperthyroidism has raised questions concerning their relationship to other goitrogens and their mode of action. Other problems have been encountered as well, particularly with respect to toxic reactions, the effect of preliminary iodine administraton, and the control of the hypothyroid state which may result. The information available on t...

UNLABELLED Focal and diffuse thyroid abnormalities are commonly encountered during the interpretation of computed tomography (CT) exams performed for various clinical purposes. These findings can often lead to a diagnostic dilemma, as the CT reflects the nonspecific appearances. Ultrasound (US) examination has a superior spatial resolution and is considered the modality of choice for thyroid ev...

BACKGROUND Pendred syndrome (PDS, MIM #274600) is an autosomal recessive disorder characterized by congenital sensorineural hearing loss and goiter. In this study, we describing the possible PDS causal mutations in a Malaysian family with 2 daughters diagnosed with bilateral hearing loss and hypothyroidism. METHODS AND RESULTS Whole exome sequencing was performed on 2 sisters with PDS and the...