Cystic fibrosis (CF) is a common inherited condition caused by mutations in the gene encoding the CF transmembrane regulator protein. With increased understanding of the molecular mechanisms underlying CF and the development of new therapies there comes the need to develop new outcome measures to assess the disease, its progression and response to treatment. As there are limitations to the curr...

OBJECTIVES This study was conducted to explore the relationships between illness perceptions, emotional representations, treatment beliefs and reported adherence in adolescents with cystic fibrosis (CF). METHODS Thirty-eight adolescents completed questionnaires assessing their perceptions of CF, beliefs about prescribed treatments and reported adherence to chest physiotherapy, enzyme suppleme...

Cystic fibrosis (CF) is the most common autosomal-recessive condition affecting the white population, with an incidence ranging between 1:2500 and 1:1800 births. It is caused by a mutation in the CFTR gene, encoding the polyprotein CF transmembrane conductance regulator (CFTR), which functions as an ATP-responsive chloride channel in the apical membrane of epithelial cells. Pathologic changes r...

IN A CONTINUOUS VISUOMOTOR TASK Shannon M. Locke 1 Michael S. Landy 1,2 Pascal Mamassian 4 Eero P. Simoncelli 1,2,3 New York University, NY: (1) Dept. of Psychology, (2) Center for Neural Science, (3) Courant Institute of Mathematical Sciences; (4) Laboratoire des Systèmes Perceptifs, CNRS UMR 8248, Département d’Études Cognitives, École Normale Supérieure, Paris, France DÉPARTEMENT D’ÉTUDES CO...

Seventy-four of 403 (18.4%) sputum isolates of Pseudomonas aeruginosa from 49 of 136 (36.0%) adults with cystic fibrosis (CF) were auxotrophic mutants. Two of 11 (18.2%) isolates of P. aeruginosa taken from patients with non-CF bronchiectasis were also auxotrophic. All 99 strains taken from non-bronchiectatic sources were prototrophic. Forty-six of 55 (83.6%) CF auxotrophs required one or more ...

Collaborative filtering (CF) is one of the most successful and widely used methods of automated product recommendation domain [1, 2, 3]. However, cardinal scale generally used for representing the preference intensity is also ineffective owing to its increasing estimation errors. In this paper, we propose a new CF-based recommendation methodology that constructs an ordinal scale-based customer ...

Jukes (1) and Broquist et al. (2) reported that the addition of formate or serine to incubating cells of an A-Methopterin-resistant strain of Xtreptococcus.faecalis increased the amount of citrovorum factor (CF, folinic acid) which was formed from pteroylglutamic acid (PGA). This finding suggested that ‘Lformate-carbon” was incorporated into the structure of CF. Under appropriate conditions an ...

Jukes (1) and Broquist et al. (2) reported that the addition of formate or serine to incubating cells of an A-Methopterin-resistant strain of Xtreptococcus.faecalis increased the amount of citrovorum factor (CF, folinic acid) which was formed from pteroylglutamic acid (PGA). This finding suggested that ‘Lformate-carbon” was incorporated into the structure of CF. Under appropriate conditions an ...

Commonly used cut-points may misclassify physical activity (PA) in people with cystic fibrosis (CF). The aim of this study was to develop and cross-validate condition-specific children adolescents CF. Thirty-five CF (15 girls; 11.6 ± 2.8 years) 28 controls (16 12.2 2.7 years), had their energy expenditure triaxial acceleration measured during six daily activities varying intensities. Euclidean ...