several authors have indicated that pcp is a toxic chemical and recalcitrant to biodegradation. aops is one of the moste effective process for degradation of persistant compound.since the mineralization of recalcitrant compound by aops (advanced oxidation processes) often requires long reaction time and strong doses of oxidant, the combination of this process with biological one, considered as ...

We report a photoresponsive monofunctionalized pillar[5]arene based on stiff stilbene. The Z isomer, Z-1, tends to form self-complexing [1]pseudorotaxanes and [c2] daisy chains, whereas the E analog, E-1, forms supramolecular polymers.

Complexing a drug may alter the rate and extent of drug absorption. The complex formation is very well applied in the administration of poorly water-soluble drugs. The drugs selected for the study are cyclooxygenase-2 inhibitors, are potent anti-infl ammatory drugs with very low water solubility. The water solubility of these drugs was enhanced by complexing with β-cyclodextrin. In vitro absorp...

Even though conventional botulinum neurotoxin (BoNT) products have shown successful treatment results in patients with benign blepharospasm (BEB), the main, potential long-term side effect of BoNT use is the development of immunologic resistance due to the production of neutralizing antibody to the neurotoxin after repeated injections. Xeomin(®) (incobotulinumtoxinA), a unique botulinum neuroto...

OBJECTIVES This review examines the pharmacologic and clinical characteristics of incobotulinumtoxinA (Xeomin(®)/Xeomeen(®)/Bocouture(®)/XEOMIN Cosmetic™; botulinum toxin type A [150 kDa]), which is free from complexing proteins, and discusses its efficacy and safety in the treatment of glabellar frown lines. Differences between incobotulinumtoxinA and other commercially available botulinum neu...