نتایج جستجو برای: complete clinical response

تعداد نتایج: 2320999  

2014
Awad Ali M Alawad

BACKGROUND The use of neoadjuvant chemotherapy in treating breast cancer has shown efficacy in downstaging primary tumors, and allows breast conservative surgery to be performed instead of mastectomy. This study aims to evaluate patterns of clinical and pathological response after two cycles of neoadjuvant chemotherapy in patients with locally advanced breast cancer. MATERIALS AND METHODS Thi...

Journal: :ESMO open 2023

The role of concurrent neoadjuvant endocrine therapy with chemotherapy in HR+HER2- breast cancer remains controversial. This systematic review and meta-analysis was conducted to better assess the efficacy safety this strategy patients cancer. trials which were randomly assigned receive alone or eligible for inclusion. Prime endpoint pathological complete response (pCR) rate. Clinical (complete ...

غفاری , جواد, نبوی , مرجان, نظری , زینب, کوثریان , مهرنوش,

Background and Purpose: chronic urticaria is a tormenter and does not have a known etiology. Association between chronic urticaria and thyroid auto-immunity has shown different results. The aim of this study is to evaluate the effect of Levo-thyroxine on the chronic urticaria and association between chronic urticaria with thyroid auto-immunity. Materials and Methods: In a prospective case-...

2016
Andrew Orton Jennifer Wright Luke Buchmann Lor Randall Ying J Hitchcock

BACKGROUND "Abscopal response" refers to the spontaneous involution of untreated metastatic disease following local primary tumor-directed therapy. We report a case of an abscopal response of untreated lung metastasis in a man with pleomorphic sarcoma of the head and neck treated with hypofractionated radiotherapy. METHODS An inoperable pleomorphic sarcoma of the postauricular soft tissue was...

2012
Moonkyoo Kong Seong Eon Hong Woo Suk Choi Si-Young Kim Jinhyun Choi

PURPOSE This study was designed to investigate the long-term oncologic outcomes for locally advanced rectal cancer patients after treatment with preoperative concurrent chemoradiotherapy followed by total mesorectal excision, and to identify prognostic factors that affect survival and pathologic response. MATERIALS AND METHODS From June 1996 to June 2009, 135 patients with locally advanced re...

2013
Andrew Zloza Joseph R Broucek Erica J Huelsmann Tasha Hughes Howard L Kaufman

Background The results of multiple IL-2 clinical trials (using a range of doses) have shown similar trends, in which IL-2 immunotherapy leads to an objective response in 15-20% of patients and complete response in 5-10%. Importantly, the majority (> 80%) of patients with a complete response maintain long-term responses. However, why only a small proportion of patients attain a complete response...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2013
N K S Cheedella A Suzuki L Xiao W L Hofstetter D M Maru T Taketa K Sudo M A Blum S H Lin J Welch J H Lee M S Bhutani D C Rice A A Vaporciyan S G Swisher J A Ajani

BACKGROUND Chemoradiation followed by surgery is the preferred treatment of localized gastroesophageal cancer (GEC). Surgery causes considerable life-altering consequences and achievement of clinical complete response (clinCR; defined as postchemoradiation [but presurgery] endoscopic biopsy negative for cancer and positron emission tomographic (PET) scan showing physiologic uptake) is an entice...

2016
Rolf-Markus Szeimies Petar Atanasov Robert Bissonnette

Complete patient clearance is often required by regulatory agencies for the approval of treatments for actinic keratosis (AK). However, an increasing number of clinicians have challenged the use of this measure in clinical practice and its interpretation. It has been argued that complete patient clearance often underestimates the clinical benefit of a drug and is influenced by a number of key c...

Journal: :acta medica iranica 0
ali asghar alavi department of thoracic surgery, tehran university of medical sciences, tehran, iran. mohsen eshraghi department of thoracic surgery, tehran university of medical sciences, tehran, iran. mohammad bagher rahim department of thoracic surgery, tehran university of medical sciences, tehran, iran. ali pasha meysami department of social medicine, tehran university of medical sciences, tehran, iran. afsaneh morteza farzan clinical research institute, tehran, iran. hanieh hajian tehran university of medical sciences, tehran, iran.

malignant pleural effusion is a common complication in certain malignancies. pleurodesis is the best option most of the time. the purpose of this study was to compare the choice of belomycin with povidone-iodine, which is not only determined by the efficacy of the agent but also by its cost, accessibility, safety, ease of administration and the number of administrations to achieve a complete re...

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