dermatomyositis (dm) is a rare idiopathic inflammatory myopathy with characteristic skin lesions. case series have shown an association between dermatomyositis and malignancy. malignancy has been found in 15-25% of the adult patients with dermatomyositis. a 50-year-old new case of breast cancer, was admitted with muscle weakness and inability to walk. physical examination revealed fever, perior...

introduction: malaria is a protozoal disease, transmitted to humans by female anopheles mosquito bite. plasmodium falciparum, compared to other kinds of plasmodium, causes more severe malaria and is associated with a higher mortality rate. annually, one to three million deaths occur due to malaria, especially by p. falciparum. case presentation: in this report, we introduce an iranian patient s...

BACKGROUND/AIMS Before tenofovir (TDF) become available in South Korea, combination therapy with entecavir (ETV) and adefovir (ADV) was the most potent regimen for chronic hepatitis B (CHB) patients who fail to respond to rescue therapy for drug resistance. We analyzed the efficacy of ETV-ADV combination therapy and investigated the clinical and clonal results of TDF-based rescue therapy in CHB...

The efficacy of single-dose combination drug therapy with diethylcarbamazine (DEC) plus albendazole (ALB), and single-drug therapy with DEC alone against geohelminths was compared as part of a mass drug administration (MDA) for elimination of filariasis. This study was conducted in two blocks of Villupuram District of Tamil Nadu State, India, covering a population of 321 000 including about 100...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 drug‑drug interactions (ddis) are one of the commonest causes of medication error in developed countries, particularly in the elderly due to poly‑therapy, with a prevalence of 20‑40%. in particular, poly‑therapy increases the complexity of therapeutic management and thereby the risk of clinically important ddis, wh...

Tumor drug resistance significantly limits the success of chemotherapy in the clinic. Tumor cells utilize multiple mechanisms to prevent the accumulation of anticancer drugs at their intracellular site of action. In this study, we investigated the anticancer efficacy of doxorubicin in combination with photodynamic therapy using methylene blue in a drug-resistant mouse tumor model. Surfactant-po...

in recent decades, by increasing complexity of drug therapy, pharmacists considered as health- care members who can help optimizing drug therapy. we know that medicines do not have the anticipated effects all the times and a vast variability may exist in their behaviors in the body. so, it is very crucial to individualize treatment for every single patient. nowadays, optimizing drug therapy in ...

background the use of metaphors rather than direct suggestions of treatment can help to weaken defense mechanisms against any functional changes and so cause an increase in the effectiveness of therapeutic interventions. conclusions since imt can repeatedly neutralize patients’ defenses without aggravating their anxiety, and as the therapy can help patients via the development of a new awarenes...