نتایج جستجو برای: combination drug eluting stents

تعداد نتایج: 937366  

Journal: :European heart journal 2005
Jörg Hausleiter Adnan Kastrati Rainer Wessely Alban Dibra Julinda Mehilli Thomas Schratzenstaller Isolde Graf Magdalena Renke-Gluszko Boris Behnisch Josef Dirschinger Erich Wintermantel Albert Schömig

AIMS Drug-eluting stents (DES) represent a major advance in interventional cardiology. Along with the success shown, current DES also present limitations related to the presence of polymer-coating, fixed drug, and dose used. With the ISAR (Individualized Drug-Eluting Stent System to Abrogate Restenosis) project, a DES system has been developed that permits individualized choice of the drug and ...

2012
Duminda N. Wijeysundera Harindra C. Wijeysundera Lingsong Yun

Background—Guidelines recommend that noncardiac surgery be delayed until 30 to 45 days after bare-metal stent implantation and 1 year after drug-eluting stent implantation. Methods and Results—We used linked registry data and population-based administrative health care databases to conduct a cohort study of 8116 patients (Ն40 years of age) who underwent major elective noncardiac surgery in Onta...

2008
Robert S. Schwartz Greg L. Kaluza Keith A. Robinson Gregory J. Wilson

Coronary drug-eluting stents are commonplace in clinical practice with acceptable safety and efficacy. Preclinical evaluation of novel drug-eluting stent technologies has great importance for understanding safety and possibly efficacy of these technologies, and well-defined preclinical testing methods clearly benefit multiple communities within the developmental, testing, and clinical evaluatio...

Journal: :Circulation 2012
Duminda N Wijeysundera Harindra C Wijeysundera Lingsong Yun Marcin Wąsowicz W Scott Beattie James L Velianou Dennis T Ko

BACKGROUND Guidelines recommend that noncardiac surgery be delayed until 30 to 45 days after bare-metal stent implantation and 1 year after drug-eluting stent implantation. METHODS AND RESULTS We used linked registry data and population-based administrative health care databases to conduct a cohort study of 8116 patients (≥40 years of age) who underwent major elective noncardiac surgery in On...

Journal: :JAMA 2014
Masahiro Natsuaki Ken Kozuma Takeshi Morimoto Hiroki Shiomi Takeshi Kimura

Two-Year Outcome of a Randomized Trial Comparing Second-Generation Drug-Eluting Stents Using Biodegradable or Durable Polymer Recentnetworkmeta-analyseshave raisedconcerns about the safety of biodegradable polymerdrug-eluting stents (BP-DES) compared with durable polymer everolimus-eluting stents (DP-EES).1-3 The NOBORI Biolimus-Eluting vs XIENCE/ PROMUSEverolimus-ElutingStentTrial (NEXT) is a9...

2012
Nic Debusschere Matthieu De Beule Patrick Segers Peter Dubruel Benedict Verhegghe

Biodegradable stents are a promising technological development, as they temporarily support the stenotic blood vessel during its healing period, leaving no obstacle for possible future interventions and avoiding long term side effects of conventional drug eluting stents. Moreover, the biodegradable stent material forms an ideal vehicle for local drug delivery [1]. Finite element computer simula...

Journal: :International journal of clinical and experimental medicine 2010
Xiaodong Ma Tim Wu Michael P Robich Xingwei Wang Hao Wu Bryan Buchholz Stephen McCarthy

Coronary artery disease (CAD) is currently a leading cause of death worldwide. Drug-eluting stents (DESs) have been dominant for the treatment of CAD in the interventional cardiology world owing to their efficacy in significantly reducing restenosis. However, late stage stent thrombosis has become a major concern. Stent platform, drug delivery vehicle and type of drug are three parts of DES and...

2007
Adnan Kastrati

c s c u r r d t m t p s p a t l t a B b w d a t a 0 d S o s rug-eluting stents have been the most successful strategy or the prevention of restenosis after percutaneous coronary nterventions (1). In line with this, the STRATEGY Single High-Dose Bolus Tirofiban and Sirolimus Eluting tent versus Abciximab and Bare Metal Stent in Acute yocardial Infarction) study showed a marked decrease in he nee...

Journal: :Heart 2003
R Virmani F D Kolodgie A Farb A Lafont

Animal models of stenting probably predict human responses as the stages of healing are remarkably similar. What is characteristically different is the temporal response to healing, which is substantially prolonged in humans. The prevention of restenosis in recent clinical trials of drug eluting stents may represent a near absent or incomplete phase of intimal healing. Continued long term follo...

2017
Jinghang Li

Heart disease is a common medical condition that affects hundreds of thousands of people each year in the United States alone. In response, scientists have spent decades researching technologies to treat this disease. Coronary stents are a technology developed to keep collapsing heart vessels open to promote proper blood flow and prevent further cardiovascular complications. Since the 1970s, th...

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