This contribution, based on a Special Interest Group session held during IMC9, focuses on physiological based models of filamentous fungal colony growth and interactions. Fungi are known to be an important component of ecosystems, in terms of colony dynamics and interactions within and between trophic levels. We outline some of the essential components necessary to develop a fungal ecology: a m...

Concentrations of ethanol similar to those in the blood of intoxicated patients suppressed phytohemagglutinin- or streptolysin O-induced lymphocyte transformation, and inhibited bone marrow granulocyte colony growth in soft agar. Inhibition of lymphocyte transformation and granulocyte colony growth occurred despite the presence of large concentrations of folate and other vitamins. These in vitr...

Human granulocyte-macrophage colony-stimulating factor (GM-CSF) exerts profound effects on the proliferation, differentiation, and effector function of myeloid lineage cells. In contrast to its growth-promoting effects on normal myeloid progenitor cells, we found that GM-CSF unexpectedly inhibited the colony growth of U937 cells in agar culture. Furthermore, medium conditioned by recombinant GM...

lnterleukin-3 (11-3) is one of the hematopoietic growth factors that regulates the growth and differentiation of pluripotent stem cells, thereby leading to the production of all the major blood cell types. The role of 11-3 in the regulation of pulmonary alveolar macrophage (PAM) production was investigated. 11-3 stimulated the proliferation and clonal growth of murine PAM with a dose-response c...

background: acute myeloid leukemia (aml) is an immunophenotypically heterogeneous malignant disease, in which cd34 positivity is associated with poor prognosis. osteopontin (opn) plays different roles in physiologic and pathologic conditions like: survival, metastasis and cell protection from cytotoxic and apoptotic stimuli. due to anti-apoptotic effect of opn in normal and malignant cells, sil...

Human cord blood was used as a source of progenitor and stem cells to evaluate the effect of recombinant human stem-cell factor (SCF) on colony formation and the generation of colony-forming cells (CFC) under highly defined, serum-deprived conditions. SCF interacted with a number of hematopoietic growth factors to stimulate colony growth and was particularly effective in stimulating the formati...

Autonomous release of hematopoietic growth factors may play a crucial role in the pathogenesis of certain hematological malignancies. Because of its cytokine synthesis-inhibiting action, interleukin 10 (IL-10) could be a potentially useful molecule to affect leukemic cell growth in such disorders. Chronic myelomonocytic leukemia (CMML) cells spontaneously form myeloid colonies (colony-forming u...

The modular construction of colonial organisms can generate complex growth patterns that incorporate both growth and partial mortality. These patterns often confound simple age based descriptions of growth but, in some cases, modularity can generate predictable patterns of colony growth that are amenable to modeling approaches more commonly used in unitary organisms. Colonies of the Caribbean g...

Although density-dependent benefits to hemipterans from ant tending have been measured many times, few studies have focused on integrated effects such as interactions between ant tending, natural enemy density, and hemipteran density. In this study, we tested whether the invasive mealybug Phenacoccus solenopsis is affected by tending by ghost ants (Tapinoma melanocephalum), the presence of para...

In response to intraand interspecific competition, ant colonies have evolved mechanisms to maximize early colony growth. Through the analysis of photographic images, this study describes the individual effect of two different strategies, pleometrosis and pupae transplantation, on the growth of Lasius niger colonies. Results showed that both methods had an overall positive effect on colony produ...