نتایج جستجو برای: collagen induced arthritis

تعداد نتایج: 1103161  

Journal: :Arthritis Research & Therapy 2006
Stefan Carlsen Kutty Selva Nandakumar Rikard Holmdahl

Joint cartilage is attacked in both autoimmune inflammatory and osteoarthritic processes. Type IX collagen (CIX) is a protein of importance for cartilage integrity and stability. In this study we have backcrossed a transgenic disruption of the col9a1 gene, which leads to an absence of CIX, into two different inbred mouse strains, DBA/1 and B10.Q. None of the CIX-deficient mice developed observa...

Journal: :Journal of immunology 2011
Van C Willis Alison M Gizinski Nirmal K Banda Corey P Causey Bryan Knuckley Kristen N Cordova Yuan Luo Brandt Levitt Magdalena Glogowska Piyanka Chandra Liudmila Kulik William H Robinson William P Arend Paul R Thompson V Michael Holers

Rheumatoid arthritis is associated with the development of autoantibodies to citrullinated self-proteins. Citrullinated synovial proteins, which are generated via the actions of the protein arginine deiminases (PADs), are known to develop in the murine collagen-induced arthritis (CIA) model of inflammatory arthritis. Given these findings, we evaluated whether N-α-benzoyl-N5-(2-chloro-1-iminoeth...

Journal: :Journal of Experimental Medicine 1983

Journal: :Applied sciences 2021

Cudrania tricuspidata extracts (CTE) and Stewartia koreana (SKE) are viable drugs for managing inflammation. We investigated the nitric oxide levels of CTE a mixture CTE/SKE (CTE mix) against lipopolysaccharide-induced RAW264.7 cells. In addition, we administered mix to mice with collagen-induced arthritis confirm an anti-inflammatory effect rheumatoid arthritis. analyzed symptoms by oral admin...

Journal: :Japanese Journal of Pharmacology 2000

Journal: :Zahedan Journal of Research in Medical Sciences 2017

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