نتایج جستجو برای: cognitiveimpairment cranial irradiation

تعداد نتایج: 89231  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2012
Yani Zou Rikki Corniola David Leu Aslam Khan Peyman Sahbaie Ayanabha Chakraborti David J Clark John R Fike Ting-Ting Huang

Cranial irradiation is widely used in cancer therapy, but it often causes cognitive defects in cancer survivors. Oxidative stress is considered a major cause of tissue injury from irradiation. However, in an earlier study mice deficient in the antioxidant enzyme extracellular superoxide dismutase (EC-SOD KO) showed reduced sensitivity to radiation-induced defects in hippocampal functions. To fu...

2013
Tomohiko Tanino Yoshiko Kanasaki Takatoshi Tahara Koichi Michimoto Kazuhiko Kodani Suguru Kakite Toshio Kaminou Takashi Watanabe Toshihide Ogawa

BACKGROUND Although there are many reports regarding radiation-induced microbleeds, its frequency, relation to dose and latency after radiation are not fully elucidated. The purpose of this study was to evaluate the frequency, latency, patient factors and dose relation of radiation-induced microbleeds after cranial irradiation using phase-sensitive magnetic resonance imaging (PSI) at 3.0 T. M...

Journal: :International Journal of Radiation Oncology*Biology*Physics 2017

Journal: :Indian Journal of Medical and Paediatric Oncology 2015

2012
Gustavo Arruda Viani André Campiolo Boin Veridiana Yuri Ikeda Bruno Silveira Vianna Rondinelli Salvador Silva Fernando Santanella

Objective: To determine the role of prophylactic cranial irradiation (PCI) in patients with small cell lung cancer (SCLC). Methods: We searched various databases, selecting randomized clinical trials published in journals or conference proceedings within the last 30 years and investigating the role of PCI in the mortality of patients with SCLC, submitted to PCI or not. Results: Sixteen randomiz...

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