نتایج جستجو برای: cognition disorders

تعداد نتایج: 711786  

Journal: :Sleep Medicine Reviews 2021

Central disorders of hypersomnolence (CDH) are characterized by excessive daytime sleepiness not related to comorbid sleep or medical disturbances. We systematically examined scientific literature on cognitive functions in patients suffering from CDH. Forty-eight studies proved eligible and were analyzed separately for Narcolepsy Type 1 (NT1), 2 (NT2), Idiopathic hypersomnia (IH) Kleine-Levin s...

2009
Anna C Need Deborah K Attix Jill M McEvoy Elizabeth T Cirulli Kristen L Linney Priscilla Hunt Dongliang Ge Erin L Heinzen Jessica M Maia Kevin V Shianna

Psychiatric disorders such as schizophrenia are commonly accompanied by cognitive impairments that are treatment resistant and crucial to functional outcome. There has been great interest in studying cognitive measures as endophenotypes for psychiatric disorders, with the hope that their genetic basis will be clearer. To investigate this, we performed a genome-wide association study involving 1...

2017
Yuko Higuchi Tomiki Sumiyoshi Tomonori Seo Motomu Suga Tsutomu Takahashi Shimako Nishiyama Yuko Komori Kiyoto Kasai Michio Suzuki

Cognitive function is impaired in patients with schizophrenia-spectrum disorders, even in their prodromal stages. Specifically, the assessment of cognitive abilities related to daily-living functioning, or functional capacity, is important to predict long-term outcome. In this study, we sought to determine the validity of the Schizophrenia Cognition Rating Scale (SCoRS) Japanese version, an int...

Journal: :Human molecular genetics 2009
Anna C Need Deborah K Attix Jill M McEvoy Elizabeth T Cirulli Kristen L Linney Priscilla Hunt Dongliang Ge Erin L Heinzen Jessica M Maia Kevin V Shianna Michael E Weale Lynn F Cherkas Gail Clement Tim D Spector Greg Gibson David B Goldstein

Psychiatric disorders such as schizophrenia are commonly accompanied by cognitive impairments that are treatment resistant and crucial to functional outcome. There has been great interest in studying cognitive measures as endophenotypes for psychiatric disorders, with the hope that their genetic basis will be clearer. To investigate this, we performed a genome-wide association study involving 1...

Journal: :North American journal of medicine & science 2011
William S Stone Lisa Iguchi

STUDY BACKGROUND: Schizophrenia and autism are both neurodevelopmental disorders that were once considered to be the same disorder expressed in different developmental periods. Although they were separated diagnostically about 40 years ago, they share several clinical and possibly, etiological features. This paper reviews overlaps in four domains of function to consider the issue of whether the...

Journal: :European Neuropsychopharmacology 2015
Noriko Yoshimi Takashi Futamura Kenji Hashimoto

Cognitive impairment, including impaired social cognition, is largely responsible for the deterioration in social life suffered by patients with psychiatric disorders, such as schizophrenia and major depressive disorder (MDD). Brexpiprazole (7-{4-[4-(1-benzothiophen-4-yl)piperazin-1-yl]butoxy}quinolin-2(1H)-one), a novel serotonin-dopamine activity modulator, was developed to offer efficacious ...

Journal: :Journal of neurophysiology 2016
Christopher M Filley R Douglas Fields

Whereas the cerebral cortex has long been regarded by neuroscientists as the major locus of cognitive function, the white matter of the brain is increasingly recognized as equally critical for cognition. White matter comprises half of the brain, has expanded more than gray matter in evolution, and forms an indispensable component of distributed neural networks that subserve neurobehavioral oper...

2017
Nora M. Raschle Lynn V. Fehlbaum Willeke M. Menks Felix Euler Philipp Sterzer Christina Stadler

The human brain has the capacity to integrate various sources of information and continuously adapts our behavior according to situational needs in order to allow a healthy functioning. Emotion-cognition interactions are a key example for such integrative processing. However, the neuronal correlates investigating the effects of emotion on cognition remain to be explored and replication studies ...

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