نتایج جستجو برای: codon usage
تعداد نتایج: 114780 فیلتر نتایج به سال:
It has become clear that in most bacterial species there is considerable heterogeneity in codon usage among genes, and the codon usage of any gene is thought to reflect a balance between the forces of mutation, selection, and random genetic drift [4]. The strength and direction of these forces vary for different species, depending on their lifestyles [1]. In this study, we investigated the leve...
Viruses have to exploit host transcription and translation mechanisms to replicate in a hostile host cellular environment, and therefore, it is likely that the infected host may impose pressure on viral evolution. In this study, we investigated differences in codon usage preferences among the highly mutable single strain RNA viruses which infect vertebrate or invertebrate hosts, respectively. W...
Codon usage adaptation of lytic viruses to their hosts is determinant for viral fitness. In this work, we analyzed the codon usage of adenoviral proteins by principal component analysis and assessed their codon adaptation to the host. We observed a general clustering of adenoviral proteins according to their function. However, there was a significant variation in the codon preference between th...
Selective Factors Associated with the Evolution of Codon Usage in Natural Populations of Arboviruses
Arboviruses (arthropod borne viruses) have life cycles that include both vertebrate and invertebrate hosts with substantial differences in vector and host specificity between different viruses. Most arboviruses utilize RNA for their genetic material and are completely dependent on host tRNAs for their translation, suggesting that virus codon usage could be a target for selection. In the current...
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