The induction of polyploidy is considered the reproductive end of cells, but there is evidence that polyploid giant cancer cells (PGCCs) contribute to cell repopulation during tumor relapse. However, the role of these cells in the development, progression and response to therapy in colon cancer remains undefined. Therefore, the main objective of this study was to investigate the generation of P...

The tosyl functional group is commonly used in carbohydrate chemistry as a nucleofuge. Tosylation of the primary hydroxyls carbohydrates are generally performed after orthogonal protection/deprotection reactions. However, it can be done regioselectively from unprotected sugars. Several examples have been described literature starting free monosaccharides. Yields good but may vary according to n...

Abstract. The Michelson Interferometer for Passive Atmospheric Sounding (MIPAS) measured the middle-infrared limb emission spectrum of atmosphere from 2002 to 2012 on board ENVISAT, a polar-orbiting satellite. Recently, European Space Agency (ESA) completed final reprocessing MIPAS measurements, using version 8 level 1 and 2 processors, which include more accurate models, processing strategies,...

the vase life of cut flowers prolong by some compounds, which can improve their hormonal regulation and water relations or reduce microbial growth in xylem tissu. the effect of chemical treatments on vase life longevity of rose 'ilona'. a randomized complete block design with three replications conducted with following the treatments of control, sts , nickel sulfate, cobalt chloride, ...

Heat shock proteins (HSPs) are critical for adaptation to hypoxia and/or ischemia. Previously, we demonstrated that cobalt chloride (CoCl2), a well-known hypoxia mimetic agent, is an inducer of HSP90. In the present study, we tested the hypothesis that CoCl₂-induced upregulation of HSP90 is able to provide cardioprotection in serum and glucose-deprived H9c2 cardiomyocytes (H9c2 cells). Cell via...

the preparation of nanostructure type manganese oxide and cobalt oxide materials with the smallest particle size is reported here. the nanorod manganese oxide and cobalt oxide nanotube were prepared via a sol-gel reaction in reverse micelles from kmno4 and cocl2 with respectively source at room-temperature. the structure and surface morphology of the obtained manganese oxide were studied by mea...

A simple and efficient method has been developed for the synthesis of alpha-aminonitriles by a one-pot three- component condensation of aldehydes, amines, and potassium cyanide in acetonitrile in the presence of a catalytic amount of CoCl2 at room temperature.

Previous studies from our group have demonstrated that sevoflurane post-conditioning (SPC) protects against myocardial ischemia reperfusion injury via elevating the intranuclear expression of hypoxia inducible factor-1 alpha (HIF-1α). However, diabetic SPC is associated with decreased myocardial protection and disruption of the HIF-1 signaling pathway. Previous studies have demonstrated that co...

Ischaemic heart disease is the main cause of death in western countries. Cardiac tissue is primarily damaged by cardiomyocyte cell death triggered by low oxygen supply to the heart (hypoxia). The current therapeutic approach is coronary angioplastic intervention or thrombolytic treatments to resume blood flow in the ischaemic heart. Unfortunately, reperfusion itself causes a burst of ROS produc...

En el presente trabajo realizamos un estudio voltamperométrico del proceso de depósito cobalto sobre substrato oro a partir baño electrolito base bitartratos y composición CoCl2 0.01 M + KC4H5O6 0.05 M. Los resultados indican que, sistema estudiado, se puede electro depositar en rango potencial ubicado entre -0.5 -0.9 V. El comportamiento la corriente pico vs velocidad barrido1/2, sugiere contr...