The effort to improve the identification and management of patients with chronic kidney disease (CKD) is based on implementing more precise means of assessing kidney function and kidney damage in the clinical setting. Over the past decade, the clinical chemistry community has adopted routine reporting of estimated GFR (eGFR) calculated from the Modification of Diet in Renal Disease (MDRD) Study...

Objective: To assess CKD prevalence and risk factors including socio-demography among diabetics by estimating GFR rather than serum creatinine (sCr).
 Methods: A cross-sectional study was conducted in Dec. 15 2019 through Aug. 2020, 800 attending tertiary diabetes centers, Baghdad. Data collected self-administered questionnaire. SPSS used for data analysis (mean, standard deviation T-test)...

Mục tiêu: Khảo sát mối liên hệ giữa một số xét nghiệm sinh hóa và thông học với chỉ lọc cầu thận thiết lập bởi các công thức Cockcroft – Gault, MDRD, CKD EPI 2009, độ thanh thải creatinine 24 giờ trên đối tượng suy mạn.Phương pháp nghiên cứu: Cắt ngang mô tả 44 người là dân Việt Nam, từ đủ 18 tuổi trở lên mắc bệnh mạn đến khám tại phòng Khám thận, Bệnh viện Đại Y Dược cơ sở 2.Kết quả: Độ tương ...

BACKGROUND Glomerular filtration rate (GFR)-estimating equations are used to determine the prevalence of chronic kidney disease (CKD) in population-based studies. However, it has been suggested that since the commonly used GFR equations were originally developed from samples of patients with CKD, they underestimate GFR in healthy populations. Few studies have made side-by-side comparisons of th...

AIM To validate the accuracy of estimated glomerular filtration rate (eGFR) equations in Malay population attending our hospital in comparison with radiolabeled measured GFR. METHODS A cross-sectional study recruiting volunteered patients in the outpatient setting. Chromium EDTA (51Cr-EDTA) was used as measured GFR. The predictive capabilities of Cockcroft-Gault equation corrected for body su...

BACKGROUND Various estimating equations have been developed to estimate glomerular filtration rate (GFR) for use in clinical practice. However, the unique renal physiological and pathological processes that occur in sickle cell disease (SCD) may invalidate these estimates in this patient population. This study aims to compare GFR estimated using common existing GFR predictive equations to actua...

Chronic kidney disease (CKD) is a common health problem worldwide. CKD staging or classification, together with patients’ prognosis and treatment plan depend on the patients’ kidney function which is assessed by measurement of glomerular filtration rate (GFR). Estimated GFR can be obtained using serum or plasma creatinine as a main variable in equations or formulae such as Cockcroft-Gault equat...

BACKGROUND The performance of the Cockcroft-Gault (CG) equation, the Modification of Diet in Renal Disease (MDRD) formula, and the Chronic Kidney Disease Epidemiology Collaboration equation (CKD-EPI) was evaluated in body mass index (BMI) categories. MATERIAL AND METHODS In this retrospective cohort study in diabetic patients, creatinine clearance was measured by collecting 24-hour urines. Re...

BACKGROUND The determination of kidney function plays a pivotal role in living donors renal assessment because of the long-term hazards of life with one kidney. Guidelines recommend estimation of glomerular filtration rate (GFR) by the Modification of Renal Disease (MDRD) or Cockroft-Gault equations for people with normal or near-normal renal function. Cystatin C (CysC) has been introduced as a...