Our cyanylation (CN)-based methodology for determining disulfide structure of cystinyl proteins overcomes the limitations of conventional proteolytic methods. However, the CN-based method has the potential drawback that occasionally some CN-induced cleavage fragments may not be detected. We show that CN-based methods can overcome the failure to detect fragments by demonstrating the existence of...

Dedicated to Professor Heinrich Nöth on the occasion of his 85th birthday Recrystallization of silver pentacyanocyclopentadienide Ag[C5(CN)5] from N,N-dimethylformamide (DMF) gives the polymeric 1 : 1 complex [Ag{C5(CN)5}(DMF)] (1). The Ag+ cation is coordinated by three N atoms of three different [C5(CN)5] anions and two O atoms of two DMF molecules. Each [C5(CN)5] is coordinated via three nei...

Using the computational approach introduced in [Agore A.L., Bontea C.G., Militaru G., J. Algebra Appl. 12 (2013), 1250227, 24 pages] we classify all coalgebra split extensions of H4 by k[Cn], where Cn is the cyclic group of order n and H4 is Sweedler’s 4-dimensional Hopf algebra. Equivalently, we classify all crossed products of Hopf algebras H4#k[Cn] by explicitly computing two classifying obj...

Slight changes in the coordination structure of the manganese(v)-nitrido anionic complex, [MnV(N)(CN)4]2-, induced by using a "lipid package" approach markedly made an impact on the corresponding redox potentials. The single crystals of four lipid assemblies, [dabco-(CH2)n-1-CH3]2[Mn(N)(CN)4(H2O)]·xH2O (n = 15, 16, 17 and 18; dabco = 1,4-diazabicyclo[2,2,2]octane), were synthesized and solid-st...

We synthesized an indolium–coumarin dyad (1) and its derivatives with –Cl (2), –N(CH3)2 (3), or –NO2 (4) substituent, and used them for fluorometric detection of cyanide anions (CN(-)) in aqueous media. All of the dyads exhibit fluorescence enhancement by CN(-) via a nucleophilic interaction of CN(-) with the indolium carbon atoms. Their fluorescence response and selectivity to CN(-), however, ...

A graphene/nitrogen-enriched sandwiched composite (HAT-CN/Gr) as readily obtained from in-situ combination of HAT-CN and GO through sonication thermal reduction. The resultant HAT-CN/Gr cathode exhibits excellent lithium storage performance.

Ser/thr phosphatases dephosphorylate their targets with high specificity, yet the structural and sequence determinants of phosphosite recognition are poorly understood. Calcineurin (CN) is a conserved Ca(2+)/calmodulin-dependent ser/thr phosphatase and the target of immunosuppressants, FK506 and cyclosporin A (CSA). To investigate CN substrate recognition we used X-ray crystallography, biochemi...

Transient electronic and vibrational absorption spectroscopy unravel the mechanisms and dynamics of bimolecular reactions of CN radicals with acetone in deuterated chloroform solutions. The CN radicals are produced by ultrafast ultraviolet photolysis of dissolved ICN. Two reactive forms of CN radicals are distinguished by their electronic absorption bands: "free" (uncomplexed) CN radicals, and ...

Cationorm® (CN) cationic nanoemulsion was demonstrated to enhance tear film (TF) stability in vivo possibly via effects on tear film lipid layer (TFLL). Therefore the interactions of CN with human meibum (MGS) and TFLL in vitro and in vivo deserve special study. MGS and CN were spread at the air/water interface of a Langmuir surface balance to ensure a range of MGS/CN oil phase ratios: 20/1, 10...