CirCulating MelanoMa Cells Molecular markers have been increasingly applied in cancer to assess metastatic risk and to guide treatment, including in melanoma, where assessment of BRAF mutations in tumor tissues to determine suitability for treatment with vemurafenib is now routine (1). Static assessment of tumor tissues, however, does not indicate whether tumor cells are being shed or whether t...

The increased diffusion of the Internet has made computer-mediated communication (CMC) very popular. However, a difficult question arises for psychologists and communication researchers: "What are the communicative characteristics of CMC?" According to the "cues-filtered-out" approach, CMC lacks the specifically relational features (social cues), which enable the interlocutors to identify corre...

Children with medical complexity (CMC) are a growing population of diagnostically heterogeneous children characterized by chronic conditions affecting multiple organ systems, the use of medical technology at home as well as intensive healthcare service utilization. Many of these children will experience either a respiratory-related complication and/or they will become established on respiratory...

Posterior carpometacarpal (CMC) dislocation is a rare condition. Treatment is usually surgical though no strict consensus can be found upon literature review. If diagnosed early and no associated fractures are found, CMC dislocation could benefit from conservative treatment comprising closed reduction and splint immobilisation. We report the case of a 26-year-old man diagnosed with a posterior ...

The interaction between disjunctive interpersonal relationships, those where the parties to the relationship disagree on the goals of the relationship, and the use of computer mediated communications channels is a relatively unexplored domain. Bargh (2002) suggests that CMC channels can amplify the development of interpersonal relationships, and notes that the effect is not constant across comm...

Code-message coevolution (CMC) models represent coevolution of a genetic code and a population of protein-coding genes ("messages"). Formally, CMC models are sets of quasispecies coupled together for fitness through a shared genetic code. Although CMC models display plausible explanations for the origin of multiple genetic code traits by natural selection, useful modern implementations of CMC m...

The potential of Computer-Mediated Communication (CMC) to enable new forms of social interaction and foster democratisation of decision making has raised much interest but has been challenged by contradictory research results. Conceived as a tool, CMC was examined in terms of its social effects thus indicating a degree of technological determinism. In this paper, we explore CMC as an extension ...

A cellulase producing bacterium (E3 strain) was isolated from fecal matter of elephant and identified as Bacillus sp. using 16S rDNA sequenced based molecular phylogenetic approach. While studying the effect of substrates like Carboxymethyl cellulose (CMC), avicel, starch, maltose, sucrose, glucose, fructose, galactose and lactose on cellulase production, it was found that CMC was best carbon s...

For each embedded constant mean curvature surface in R 3 with three ends and genus zero, we construct a conjugate cousin boundary contour in S 3. The moduli space of such contours is parametrized by the space of triples of distinct points in S 2. This imposes necessary conditions on the cmc surfaces; moreover, we expect the space of triples exactly parametrizes their moduli space. Our approach ...