BACKGROUND The causative role of diffuse macular edema in various etiologies is often undetermined. OBJECTIVES To describe an association between extrafoveal vitreous traction and non-diabetic diffuse macular edema secondary to various ocular entities. METHODS In a retrospective study of eyes with non-diabetic diffuse macular edema, charts and optical coherence tomography scans demonstratin...

Diabetic macular edema represents one of the most important causes of visual morbidity in diabetes mellitus. The National Diabetes Information Clearinghouse estimates the prevalence of diabetes mellitus types 1 and 2 at 11.3% of the population above the age of 20, with an annual incidence of 1.9 million cases in the United States alone. In this population, the prevalence of diabetic macular ede...

PURPOSE The purpose of the study was to investigate the effect of orally administered ruboxistaurin (RBX, LY333531), a selective protein kinase C beta inhibitor, on the permeability of the blood-retinal barrier in patients with diabetic macular edema. METHODS Forty-one patients with diabetic macular edema were randomly assigned to an 18-month randomized, placebo-controlled, double-masked tria...

PURPOSE To assess the efficacy of intravitreal use of triamcinolone acetonide combined with laser photocoagulation for the treatment of diffuse diabetic macular edema and to compare it with the separate use of each treatment. METHODS After systemic clinical control, thirty patients with diffuse diabetic macular edema were divided into 3 treatment groups: (1) macular grid photocoagulation; (2)...

PURPOSE To determine whether or not a sub-Tenon's capsule injection of triamcinolone acetonide(TA) is an effective treatment for refractory diabetic macular edema after vitrectomy. METHODS Thirty-nine eyes of 26 patients with diabetic macular edema were injected with 20 mg TA into the sub-Tenon's capsule. The central macular thickness (CMT) measured by an optical coherence tomography (OCT) an...

BACKGROUND Diabetes mellitus remains the leading cause of blindness among working age Americans with diabetic macular edema being the most common cause for moderate and severe vision loss. OBJECTIVE To investigate the anatomical and visual benefits of pars plana vitrectomy with inner limiting membrane peeling in patients with nontractional diabetic macular edema as well as correlation of inte...

Macular edema is the leading cause of vision loss in increasingly frequent occurrence diabetes mellitus, a true epidemic developed countries. Diabetic macular closely related to lifestyle, obesity, smoking or high blood pressure. oedema people with countries, and its prevalence directly duration diabetes. Its incidence varies from publication publication, ranging between 7.5% 15.2%, more common...

BACKGROUND We evaluated the efficacy of intravitreal bevacizumab on diabetic macular edema with subfoveal and perifoveal hard exudates. MATERIALS AND METHODS Eleven eyes (11 patients) exhibiting diabetic macular edema with subfoveal and perifoveal hard exudates were included in this prospective, nonrandomized interventional pilot study. All patients were treated with monthly scheduled intravi...

OBJECTIVES Diabetic macular edema results in irreversible loss of vision and is the major cause of visual morbidity in patients with Diabetes of adult onset. DCCT trial has linked this to poorer control and increased duration of DM. laser treatment in such cases is known to reduce visual impairment by 50% for a period of 5 years. The aim of this study is to evaluate the effect of laser on visua...

OBJECTIVE We examined the endothelial nitric oxide (eNOS) gene polymorphisms to assess its possible association with diabetic retinopathy and macular edema. RESEARCH DESIGN AND METHODS A total of 226 patients with type 2 diabetes and 186 healthy subjects were studied. Type 2 diabetic patients consisted of 110 patients without retinopathy, 46 patients with nonproliferative diabetic retinopathy...