نتایج جستجو برای: clinical trial committee
تعداد نتایج: 1404691 فیلتر نتایج به سال:
Background: Pityriasis rosea is an acute, inflammatory and self-limited disease, which is characterized by a primary scaly plaque (Herald patch) followed by a generalized, symmetrical papulosqumous eruption (Mostly on trunk and proximal extremities). Objective: To determine the efficacy of erythromycin in the treatment of patients with pityriasis rosea. Patients and Methods: In this doubl...
A novel Protocol Ethics Tool Kit ('Ethics Tool Kit') has been developed by a multi-stakeholder group of the Multi-Regional Clinical Trials Center of Brigham and Women's Hospital and Harvard. The purpose of the Ethics Tool Kit is to facilitate effective recognition, consideration and deliberation of critical ethical issues in clinical trial protocols. The Ethics Tool Kit may be used by investiga...
Healthy volunteers are the first group who take part in experimental studies on the efficacy of new drugs. Parallel with expanding the boundaries of medical science, medical research has shown rapid growth which has caused new and critical ethical challenges in medical research.A clinical trial is one of the essential methods in clinical research and a very challenging method from the ethical v...
BACKGROUND The Alveolar Recruitment for Acute Respiratory Distress Syndrome Trial (ART) is an international multicenter randomized pragmatic controlled trial with allocation concealment involving 120 intensive care units in Brazil, Argentina, Colombia, Italy, Poland, Portugal, Malaysia, Spain, and Uruguay. The primary objective of ART is to determine whether maximum stepwise alveolar recruitmen...
IN the autumn of 1944 a small committee was formed in Belfast to investigate the clinical applications of penicillin, and for various research projects special supplies of penicillin were received from the Medical Research Council of Great Britain. In February, 1945, the committee agreed to accept responsibility in Northern Ireland for a thorough clinical trial of penicillin in subacute bacteri...
Glioblastoma is the most common primary brain malignancy and is associated with poor prognosis despite aggressive local and systemic therapy, which is related to a paucity of viable treatment options in both the newly diagnosed and recurrent settings. Even so, the rapidly increasing number of targeted therapies being evaluated in oncology clinical trials offers hope for the future. Given the br...
abstract background: premenstrual syndrome (pms) can cause problems in daily work and relationships. materials and methods: eighty‑six women were randomly assigned to two intervention groups and one control group. patients were asked to fill out the pms daily symptoms record for 2 months, and then the participants were randomly assigned to one of the three study groups. medical intervention was...
objectives : the aim of this randomized clinical trial was to assess the efficacy of memantine versus methylphenidate in the treatment of children with attention deficit hyperactivity disorder. method : forty participants (34 boys and 6 girls) aged 6-11 who were diagnosed with attention deficit hyperactivity disorder based on (dsm-iv-tr) criteria were selected for this study. the participants w...
abstract backgrounds: subacromial impingement is a common cause of shoulder pain and many patients with this condition recover with conservative management. the most commonly used modalities of nonoperative treatment include activity modification, anti-inflammatory medication and subacromial injection of steroid and ultrasound and physical therapy programs. this study assessed the value of phys...
objectives in this section, we studied dietary and other factors related to the effect of lifestyle in type 2 diabetes. these factors may affect the incidence of type 2 diabetes which could be corrected by lifestyle modifications. background prevalence of type 2 diabetes is increasing rapidly worldwide. recent data is reprehensive of increasing diabetes prevalence from 285 millions in 2010 (6.4...
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