most contemporary clinical reasoning tests typically assess non-automatic thinking. therefore, a test is needed to measure automatic reasoning or pattern recognition, which has been largely neglected in clinical reasoning tests. the puzzle test (pt) is dedicated to assess automatic clinical reasoning in routine situations. this test has been introduced first in 2009 by monajemi et al in the oly...

background: objective structured clinical examination (osce) is one of the best methods of evaluating the achievement of domains such as educational objectives and cognitive, emotional, and psycho-motor aspects of medical students. according to available evidences, no study has been conducted  on the evaluating of osce in midwifery students. the main purpose of this study was the evaluation of ...

clinical trial committee (ctc) has been established in food and drug organization (fdo), in 2003 to assure efficacy and safety of all types of medicinal products which are meant to be registered in iran drug list and/or obtain market authorization.all clinical trial files, meeting minutes and databases in ctc secretariat in fdo were reviewed. relevant information and data extracted, analyzed an...

background: at the present time, teaching pharmacology for medical students mainly focuses on the basic principles of pharmacology. this study was conducted to assess the current situation of pharmacology teaching and the necessity of developing clinical pharmacology from the viewpoint of medical interns and externs in tabriz university of medical sciences. methods: this descriptive cross-secti...

Abstract. MAP estimators and HPD credible sets are often criticized in the literature because of paradoxical behaviour due to a lack of invariance under reparametrization. In this paper, we propose a new version of MAP estimators and HPD credible sets that avoid this undesirable feature. Moreover, in the special case of non-informative prior, the new MAP estimators coincide with the invariant f...

Prediction accuracy of pharmacokinetic parameters is often assessed using prediction fold error, i.e., being within 2-, 3-, or n-fold of observed values. However, published studies disagree on which fold error represents an accurate prediction. In addition, "observed data" from only one clinical study are often used as the gold standard for in vitro to in vivo extrapolation (IVIVE) studies, des...