Introduction: Gold standard for alveolar cleft bone grafting is autogenous bone. Advantage of adding the growth factors to the bone is established, so adding PRF to the autogenous bone may have beneficial effects. Methods:  Platelet-rich plasma admixed with autogenous bone and as a biologic membrane over the bone grafted alveolar cleft was used. Results:  Autogenous bone in all (four cases...

PURPOSE To compare the performance in the abilities of receptive and expressive language of children with cleft lip and palate with that of children without cleft lip and palate with typical 12 to 36-month chronological development. METHOD The sample consisted of 60 children aged 12 and 36 months: 30 with cleft lip and palate diagnosis and 30 without cleft lip and palate diagnosis with typica...

BACKGROUND Retinoic acid (RA) is a key regulator of embryonic development and linked to several birth defects including cleft lip and palate (CLP). The aim was to investigate the effects of RA on proliferation and gene expression of human palatal keratinocytes (KCs) in vitro. METHODS KCs from children with and without CLP were cultured with 2 and 5 μM RA. Proliferation was measured by quantif...

Significant heterogeneity has previously been reported but with no consensus on the prevalence of dental anomalies in subjects with a cleft lip and palate (CLP), thus, the purpose of this study was to investigate the frequency of various dental anomalies in the upper dental arch in different cleft groups. Diagnostic records, i.e., panoramic, occlusal and periapical films, dental casts, and intr...

OBJECTIVES/HYPOTHESIS To evaluate the prevalence and unmet need for cleft lip-cleft palate reconstructive surgery by using incidence. Our hypotheses were that the age of presentation to screening clinics will decrease between 2006 and 2012, and the geospatial distribution of cases will expand to a more rural catchment area. STUDY DESIGN Longitudinal cross-sectional/geospatial distribution stu...

Introduction: Children with cleft lip and/or palate are at increased risk of obstructive sleep apnea. The prevalence of obstructive sleep apnea in this population is unknown. The purpose of this study was to assess the frequency of obstructive symptoms and obstructive sleep apnea diagnosis in the cleft population. We hypothesized that obstructive symptoms present more frequently in children wit...

Tooth disorders in the anterior region of the maxilla are very common among patients with cleft lip, alveolar bone and palate. The authors concentrate on dental disorders, erupting problems and root development, specifying dental anomalies - especially regarding the lateral incisor, central incisor and canine. Disorders may relate to the shape of the tooth, its location, size, number and they c...

OBJECTIVE The purpose of this study was to investigate the distribution of different cleft patterns by sex, side of the cleft, and family history of clefts in a referral hospital in the south of Spain. STUDY DESIGN One hundred twenty-three consecutive cleft lip subjects, with or without palates, attending the Stomatology Unit in the Virgen del Rocío University Hospital and in the Virgen Macar...

In this study, we analysed phonetic and phonological consonant characteristics of cleft palate speech (CPS) at ages 5 and 10 in cleft palate with/without cleft lip (CP±CL) based on Cleft Audit Protocol for Speech – Augmented (CAPS-A) data collected in the Dental Hospital in Glasgow. The nature and extent of CPS characteristics at different ages were investigated. Video-recordings of 42 cleft pa...