The contribution is concerned with a finite element formulation for the nonlinear analysis of heterogeneous solids in boundary representation. It results an arbitrary number curved edges. edges can be parametrized by, example, non-uniform rational B-splines (NURBS). presented based on scaling concept, which adopted from so-called scaled method (SBFEM). In contrast to SBFEM, proposed uses numeri...

Segments of dog carotid artery were held at in-situ length and studied in vitro after excitation of the muscle with norepinephrine and after poisoning of the muscle with potassium cyanide. In-situ length corresponded to a longitudinal strain of .57 ± .02 relative to the unstretched length. The longitudinal elastic modulus was about 4.1 X 10 dyn/cm at in-situ length and zero transmural pressure....

Unsymmetrical buckling of nonuniform circular plates with elastically restrained edge and subjected to normal pressure is studied in this paper. The asymmetric part the solution sought terms multiples harmonics angular coordinate. A numerical method employed obtain lowest load value at which waves circumferential direction can appear. effect material heterogeneity boundary on examined. For a pl...

Left ventricular (LV) ejection fraction, most commonly assessed with two-dimensional echocardiography, is an important prognostic determinant of many cardiovascular diseases. The decision of implanting specific cardiovascular devices, such as cardiac resynchronization therapy or implantable cardioverter defibrillator, recommending valvular surgery or chemotherapy relies on the LV ejection fract...

In this article, a novel spectral method based on the integral transform and finite element is introduced for nonlinear thermal analysis of hollow cylinder under asymmetric boundary excitations. The material properties are temperature-dependent vary in terms spatial coordinates. This dependency makes problem to be nonlinear. intended heat conduction equation discretized using FEM radial directi...

This paper presents a unified solution method to investigate the free vibration behaviors of laminated composite conical shell, cylindrical and an annular plate with variable thickness arbitrary boundary conditions using Haar wavelet discretization (HWDM). Theoretical formulation is established based on first-order shear deformation theory (FSDT), displacement components are extended series in ...

The continual reassessment method (CRM) is a sequential design used in phase I cancer trials to determine the maximal dose with acceptable toxicity. It has been established that the CRM is consistent under model misspecification but not generally. When the method does not converge to the target percentile, some dose-response models will be more sensitive than others in terms of how close the co...

The continual reassessment method (CRM) is a commonly used dose-finding design for phase I clinical trials. Practical applications of this method have been restricted by two limitations: (1) the requirement that the toxicity outcome needs to be observed shortly after the initiation of the treatment; and (2) the potential sensitivity to the prespecified toxicity probability at each dose. To over...

background and aims. the aim was to evaluate the effect of three methods of fiber insertion on fracture resistance of root-filled maxillary premolars in vitro. materials and methods. sixty extracted human maxillary premolars received endodontic treatment followed by preparation of mesioocclusodistal (mod) cavities, with gingival cavosurface margin 1.5 mm coronal to the cementoenamel junction (c...