INTRODUCTION The minimal cardiovascular system (CVS) model described in this study was first developed and optimized [1] to assist clinicians in diagnosing cardiovascular and circulatory dysfunction and (then) selecting reliable and appropriate therapeutic responses. This model is based on the “pressurevolume” (PV) lumped element approach. It divides the cardiovascular system in several chamber...

In this paper, we derive a comprehensive computational model to estimate the arterial pressure and the cardiac output of humans, by refining and adapting the well-established equations of the Windkessel theory. The model inputs are based on patient specific factors such as age, sex, smoking and fitness habits as well as the use of specific drugs. The model's outputs correlate very strongly with...

BACKGROUND Deaths from diseases of the circulatory system and the seasonality of deaths from these causes fell sharply between 1995 and 2005 among older age groups in Ireland. We examine whether a structural break occurred in deaths from circulatory causes in Ireland between 1995 and 2005 and test whether this can be statistically accounted for by cardiovascular prescribing during the same peri...

With the publication in 1972 of a large computer model of circulatory control, Guyton and colleagues challenged the then prevailing views on how blood pressure and cardiac output were controlled. At that time, it was widely accepted that the heart controlled cardiac output and that peripheral resistance controlled arterial blood pressure. By incorporating the empirically demonstrated concepts o...

Tujuan penelitian ini untuk mengetahui bagaimana pengembangan alat peraga sistem peredaran darah manusia dari barang bekas pada pembelajaran IPA siswa Sekolah Dasar Kelas V Tahun Pelajaran 2021/2022. Jenis adalah dan (Research and Development) menggunakan model desain 4D. Teknik pengumpulan data dalam angket lembar validasi ahli. analisis dianalisis secara deskriptif dengan interval kevalidan y...

INTRODUCTION Deep hypothermic circulatory arrest for adult aortic arch repair is still associated with significant mortality and morbidity. Furthermore, there is still significant variation in the conduct of this complex perioperative technique. This variation in deep hypothermic circulatory arrest practice has not been adequately characterized and may offer multiple opportunities for outcome e...

this manuscript is the result of ethnobotany and ethnopharmacology survey on the hezar mountain in se of iran. traditional botanical medicine is the primary mode of healthcare for most of the population of this region. the plants were collected in and around hezar mountain from 2008-2010. the authors have conducted an interview of total 75 informants; the traditional uses of 92 species belongin...

OBJECTIVE Green space has been shown to be beneficial for human wellness through multiple pathways. This study aimed to explore the contributions of neighbouring green space to cause-specific mortality. METHODS Data from 3544 Chinese men and women (aged ≥65 years at baseline) in a community-based cohort study were analysed. Outcome measures, identified from the death registry, were death from...