Anticancer activities of cinnamic acid derivatives include induction of apoptosis by irreversible DNA damage leading to cell death. The present work aimed to compare the cytotoxic and genotoxic potential of cinnamic acid in human melanoma cell line (HT-144) and human melanocyte cell line derived from blue nevus (NGM). Viability assay showed that the IC50 for HT-144 cells was 2.4 mM, while NGM c...

Analysis of phenolic compounds in sixteen Portuguese wild mushrooms species has been carried out by high-performance liquid chromatography coupled to photodiode array detector and mass spectrometer (HPLC-DAD-ESI/MS). No flavonoids were detected in the analysed samples, but diverse phenolic acids namely protocatechuic, p-hydroxybenzoic and p-coumaric acids, and two vanillic acid isomers were fou...

This review summarizes available data on argan fruit botany, geographical distribution, traditional uses, environmental interest, socioeconomic role, phytochemistry, as well as health beneficial effects and examination of future prospects. In particular, ethnomedical uses of argan fruits are carried out throughout Morocco where it has been used against various diseases. Different classes of bio...

The aim of the work was to determine main groups polyphenolic compounds in Quercus rubra L. raw materials.
 Materials and methods. leaves annual shoots Northern Red Oak used for research were collected August Lisnyky village Obuhiv district Kyiv Oblast (Ukraine). Determination component composition quantitative content flavonoids (including separately catechins), hydroxycinnamic acids, phe...

Chiral pyrrolidines and pyrrolizidines with spirooxindole ring systems are the central skeletons for numerous alkaloids and pharmacologically important compounds. Gelesmine, pseudotabersonine, formosanine, isoformosanine, morroniside and mitraphylline are some of the alkaloids containing spirooxindole ring systems. Derivatives of spirooxindole find very wide biological applications as anti micr...

An efficient one-pot three-component procedure for the synthesis of new chiral spiro oxindolopyrrolidines/pyrrolizidines with highly regio- and diastereo-enantio, selective from 1,3-dipolar cycloaddition of azomethine ylides and chiral menthol-drived trans-cinnamic are described. The mechanism of the reaction is discussed on basis of the assignment of the absolute configuration of one of the cy...

A significant proportion of the carbon fixed by plants is transported to roots and exuded rhizosphere. Exudates may have important roles in rhizosphere, such as desorbing labile phosphorus (P) or mobilizing manganese (Mn) other metal cations. This study evaluated root exudation profiles seedlings 15 eucalypt species response a P shortage if ability exude organic compounds was related Mn accumul...

chiral pyrrolidines and pyrrolizidines with spirooxindole ring systems are the central skeletons for numerous alkaloids and pharmacologically important compounds. gelesmine, pseudotabersonine, formosanine, isoformosanine, morroniside and mitraphylline are some of the alkaloids containing spirooxindole ring systems. derivatives of spirooxindole find very wide biological applications as anti micr...

Randomly collected samples of parsley and celery from different localities were analyzed to determine their quality based on arsenic concentrations, phenolic constituents the antioxidant capacity edible parts. Arsenic concentrations found in range: root (0.16 μg/g d.m.) < (0.19 leaf (0.35 (0.45 d.m.). Total contents roots similar both species varied significantly depending cultivation site: ...