The aim of this work was to evaluate the anti-Candida efficacy of twenty five molecules of plant origin. Based on their MICs, effective molecules were categorized into four categories. Susceptibility testing of test compounds was carried out by standard methodology (M27-A2) as per CLSI guidelines. Minimum Fungicidal Concentration (MFC) was determined as the lowest concentration of drug killing ...

Title: Examination of the genome-wide transcriptional response of Escherichia coli 1 O157:H7 to cinnamaldehyde exposure 2 3 Running Title: Transcriptional response of E. coli to cinnamaldehyde 4 5 6 7 Jeyachchandran Visvalingam, Juan David Hernandez-Doria and Richard A Holley* 8 9 10 Department of Food Science, University of Manitoba, Winnipeg, Manitoba, R3T 2N2, 11 Canada 12 Department of Anim...

In past work, QSAR (quantitative structure-activity relationship) models of cinnamaldehyde analogues and derivatives (CADs) have been used to predict the activities of new chemicals based on their mass concentrations, but these approaches are not without shortcomings. Therefore, molar concentrations were used instead of mass concentrations to determine antifungal activity. New QSAR models of CA...

Background: Natural preservatives are of immense importance to meet the rising demand for food with either little or no synthetic preservatives. This study has evaluated inhibitory effect cinnamaldehyde, citral and eugenol essential oil (EO) against mold growth on solid media cheese in vapour phase contact treatments. Methods: The EO at concentrations ranging from 0.06 0.25 µl/ml radial molds w...

Objective(s): To investigate the effect of cinnamaldehyde and eugenol on the telomere-dependent senescence of stem cells. In addition, to search the probable targets of mentioned phytochemicals between human telomere interacting proteins (TIPs) using in silico studies. Materials and Methods: Human adipose derived stem cells (hASCs) were studied under treatments with 2.5 µM/ml cinnamaldehyde, 0....

Four Holstein heifers (360 +/- 22 and 450 +/- 28 kg of BW in Exp. 1 and 2, respectively) fitted with ruminal trocars were used in 4 x 4 Latin square designs to evaluate the effects on ruminal microbial fermentation of the following: Exp. 1, no additive, alfalfa extract (30 g/d, AEX), a mixture of cinnamaldehyde (0.18 g/d) and eugenol (0.09 g/d; CIE1), and AEX and CIE1 in combination; and Exp. 2...

Background: Today, cancer is the leading cause of death. It appears that using large amounts natural resources reduces damaging consequences therapy. Over last decade, phytoconstituents in food have shown potential as anticancer agents. Cinnamaldehyde and its congeners their ability to act against several cancers. Objective: This article’s purpose examine cellular molecular mechanisms entail ci...

Four different plant secondary metabolites were screened for their effect on rumen biohydrogenation of forage long-chain fatty acids, using dual-flow continuous culture fermenters. Treatments were as follows: control (no additive), positive control (12 mg/L of monensin), and plant extracts (500 and 1,000 mg/L of triterpene saponin; 250 and 500 mg/L of quercetin; 250 mg/L of eugenol; 500 mg/L of...

Juvenile Hormone III is of great concern due to negative effects on major developmental and reproductive maturation in insect pests. Thus, the elucidation of enzymes involved JH III biosynthetic pathway has become increasing important in recent years. One of the enzymes in the JH III biosynthetic pathway that remains to be isolated and characterized is farnesal dehydrogenase, an enzyme responsi...