background: hyperthyroidism as a risk factor for stroke is not conclusive. there are no definite data on the relationship between ischemic cerebrovascular injury and hyperthyroidism. this study was designed to define whether the outcomes of post-ischemic stroke injury are influenced by chronic hyperthyroidism. methods: two groups of hyperthyroid (ht) and control euthyroid rats of equal numbers ...

BACKGROUND G-CSF has been shown in animal models of stroke to promote functional and structural regeneration of the central nervous system. It thus might present a therapy to promote recovery in the chronic stage after stroke. METHODS Here, we assessed the safety and tolerability of G-CSF in chronic stroke patients with concomitant vascular disease, and explored efficacy data. 41 patients wer...

2 Chronic stroke patients without residual movements of the paretic side do not respond to any available rehabilitation strategy. Recently BCI technology has been proposed for as a neurorehabilitation tool after stroke. It has been shown that learning of brain control (MEG-sensorimotor rhythm, SMR) in chronic stroke is possible but no substantial improvements in motor control and no generalizat...

Background: Stroke is the number one cause of death in Indonesia, America stroke also disability. In COVID-19, most patients experience mild to moderate respiratory symptoms, and need no specific treatment. However, some with comorbidities such as cardiovascular, diabetes mellitus, chronic disease, malignancy, it often gives serious manifestation. Objective: This study aimed profile COVID-19 at...

[Purpose] Previous studies have shown that stroke is associated with increased arterial stiffness that can be diminished by a program of physical activity. A novel exercise intervention, whole-body vibration (WBV), is reported to significantly improve arterial stiffness in healthy men and older sedentary adults. However, little is known about its efficacy in reducing arterial stiffness in chron...

BACKGROUND AND PURPOSE Infarct volume and location have a weak relationship with motor deficit in patients with chronic stroke. Recent research has focused on the relationship between spared or seemingly "healthy" neural tissue and motor function. In this study we examined MRI scans of patients with chronic stroke to determine if characteristics of seemingly normal parenchyma could predict eith...

Upper extremity hemiplegia is the primary impairment underlying stroke-induced disability. Reducing chronic hemiplegic upper extremity impairment is generally difficult, and is the impairment most frequently treated by therapists [1]. Even 3 months after stroke only 20% of the stroke survivors, however, have normal upper extremity function [2]. Whereas motor practice improves motor skill learni...

[Purpose] The purpose of this study was to evaluate the effects of a progressive resistance training (PRT) program on the walking ability of chronic stroke patients with hemiparesis following chronic stroke. [Subjects and Methods] The participants of this study were fifteen hemiplegic patients. The main outcomes measured for this study were the peak torque of the knee extensor; the gait ability...

Chronic motor deficits in the upper limb (UL) are a major contributor to disability following stroke. This study investigated the effect of short-duration robot-assisted therapy on motor impairment, as measured by clinical scales and robot-derived performance measures in patients with chronic, severe UL impairments after stroke. As part of a larger study, 15 individuals with chronic, severe UL ...

BACKGROUND Several clinical studies on chronic stroke conducted with end-effector-based robots showed improvement of the motor function in the affected arm. Compared to end-effector-based robots, exoskeleton robots provide improved guidance of the human limb and are better suited to train task-oriented movements with a large range of motions. OBJECTIVE To test whether intensive arm training w...