The aim of this article is to highlight the importance of Eccrine Spiradenoma (ES) in the differential diagnosis of chronic soft tissue lesions of the foot. These include a broad spectrum of nonneoplasm lesions, as well as benign and malignant neoplasms. Benign tumours include deep fibromatosis, neurogenic tumours, lipoma, haemangioma, synovial proliferations, and exceptionally rare on foot, sk...

Various skin and systemic symptoms may develop as a complication of treatment with different medications and medicinal substances. One of them is a relatively rare drug reaction with eosinophilia and systemic symptoms, referred to as DRESS syndrome. The morphology of skin lesions and the patient's general health can differ; the management involves withdrawal of drugs suspected of triggering DRE...

Atopic dermatitis (AD) is a chronic, recurrent inflammatory skin disorder, which is accompanied by characteristic appearance of skin lesions and intense pruritus. The etiopathogenesis of the disease has not been fully elucidated. An important role in pathophysiology of AD seems to be associated with genetically related disturbances of both structure and function of the epidermal barrier, disord...

Lobomycosis is a chronic fungal disease caused by the etiologic agent, Lacazia loboi, in the skin and subcutaneous tissues in humans and dolphins in tropical and transitional tropical climates. An Indo-Pacific bottlenose dolphin (Tursiops aduncus) stranded in Kagoshima, Japan, had severe skin lesions characterized by granulomatous reactions and hyperkeratosis that were similar to those of the l...

Background: Beta-thalassemia major (BTM) is a genetic disorder, which is common in Kerman province of Iran. New methods of care has increased their survival. Objective: The objective of this descriptive study was to assess the frequency of skin and mucosal complications of BTM patients. Patients and Methods: All BTM patients referred to Kerman-Darman Hospital in 1377 (150 cases) were evaluated....

Skin, the body’s largest organ, protects from deleterious environmental impacts (physical, chemical, microbiological) and is crucial for maintenance of temperature, electrolyte fluid balance tactile sensation, it sets a boundary between organism environment. Any change in normal skin texture disturb patient both mentally physically. Psoriasis common, chronic, recurrent inflammatory disease skin...

background: granulomatous dermatoses are common skin pathology, often need histopathological confirmation for diagnosis. histologically six sub-types of granulomas found in granulomatous skin diseases- tuberculoid, sarcoidal, necrobiotic, suppurative, foreign body & histoid type. the aims of the present study were clinico-pathological evaluation of granulomatous skin lesions and their etiol...

BACKGROUND Autoimmune hepatitis (AIH) is a form of chronic hepatitis with unclear causative factors and is characterized by immunological and auto-immunological manifestations. Several extrahepatic manifestations, such as other autoimmune disorders, are associated with AIH. AIH with dermatological conditions as the initial manifestation is rare. We report the case of AIH in which erythema nodos...

systemic lupus erythematous (sle) is an autoimmune process in which cutaneous lesions occur in majority of patients. this study was conducted to determine the pattern and prevalence of such lesions in sle in iranian children infected with sle. forty-eight patients, age between 3-16 yrs and male to female ratio of 7/1 were examined for the presence of cutaneous manifestations of sle. the most co...