OBJECTIVE To help inform primary care physicians about how to identify and slow progressive chronic renal failure. QUALITY OF EVIDENCE The National Library of Medicine (1996 to 2000) was searched using PubMed with search terms pertinent to studies on identification, course, and management of chronic renal failure. References in retrieved papers and older literature known to the authors supple...

Renal Osteodystrophy (ROD) is a common complication of chronic renal disease (CRD) and is the part of a broad spectrum of disorders of mineral metabolism that occurs in the clinical setting. It occurs early in the course of chronic renal failure and progresses as the kidney function deteriorates. It is an osseous alteration believed to arise from increased parathyroid function associated with i...

1. Water andelectrolyte status in chronic renal failure has been measured by skeletal muscle biopsy. These results have been compared with a series of muscle biopsy specimens taken from the same muscle (vastus lateralis) of normal subjects. 2. The water content, especially of the extracellular phase, is increased in chronic renal failure : the extracellular sodium and chloride contents are also...

oral mucosa can be affected in many systemic diseases such as chronic renal failure (crf). many metabolic and hematologic disorders develop in patients with crf which can also affect oral cavity. oral mucosa, teeth, salivary glands and jaw bones are affected. although hemodialysis can improve many of systemic features but the best treatment is renal transplantation. in addition to previous feat...

Muscle wasting and weakness occur frequently in patients with chronic renal failure. The mechanism(s) by which these abnormalities occur is unclear. We hypothesized that such findings were due to defective muscle protein synthesis. We measured synthetic rates of mixed muscle proteins, myosin heavy chain, and mitochondrial proteins in serial muscle biopsy samples during a continuous infusion of ...