A late dysfunction of a renal allograft refers to a progressive decline in renal function manifested)3 months after transplantation. A late dysfunction may have several causes, such as chronic rejection, chronic allograft nephropathy, chronic calcineurin inhibitor toxicity, de novo or recurrent renal disease and acute rejection. An allograft biopsy is necessary to establish a definitive diagnos...

Cyclosporine A (CsA) is highly variable pharmacokinetically and has a narrow therapeutic window; the serum level of patients treated with CsA must be monitored carefully. We investigated trough second-hour levels CsA, calculated area under curve (AUC), their association those factors chronic allograft dysfunction in pediatric patients.

In recent years, the utility of vascular complement factor 4d (C4d) deposition as diagnostic tool for antibody mediated rejection (AMR) after lung transplantation, has become a controversial issue. We aimed to pinpoint problematic nature C4d biomarker with simple experiment. quantified in broncho-alveolar lavage (BAL) transplant patients diverse post-transplant complications 3 different setting...

IntroductionTelemedicine has been successfully employed in a wide range of conditions, such as chronic lung disease and COVID-19. This study evaluate the role telemonitoring for early diagnosis acute allograft dysfunction cystic fibrosis adults who underwent transplant (LuTx). Quality life functional level achieved during 12 months follow up were assessed.MethodsPatients randomized into two gro...