نتایج جستجو برای: chronic dermal toxicity

تعداد نتایج: 622190  

Journal: :Blood 2005
Yitzhak Lippin Michal Dranitzki-Elhalel Einat Brill-Almon Chava Mei-Zahav Sarah Mizrachi Yael Liberman Adrian Iaina Eli Kaplan Eduardo Podjarny Evelyne Zeira Menahem Harati Nicole Casadevall Noam Shani Eithan Galun

Gene therapy holds a major promise. However, until now, this promise was fulfilled only in few cases, in rare genetic diseases. One very common clinical condition is anemia. Patients with anemia of chronic renal failure are treated with erythropoietin. The objective of this study was to develop a therapeutic platform for serum-secreted proteins like erythropoietin. We developed a tissue protein...

Journal: :middle east journal of cancer 0
maher soliman oncology department, faculty of medicine, alexandria university, alexandria, egypt

background: radiation-induced lung toxicity is an important dose-limiting toxicity in lung cancer radiotherapy, for which there are no generally accepted predictive factors. this study seeks to identify risk factors associated with the development of severe radiation-induced lung toxicity using clinical and dosimetric parameters. methods: we reviewed the medical records of 54 patients with hist...

Journal: :Infection and immunity 1974
S P Targowski D T Berman

Protracted inflammatory dermal reactions to staphylococcal cell walls were observed in guinea pigs passively sensitized by transfer of peritoneal exudate cells but not by immune serum from guinea pigs actively sensitized with heat-killed cells of Staphylococcus aureus. The experiments verify the hypothesis that the protracted reaction is a cell-mediated immune response which is resolvable from ...

Journal: :Journal of the Royal Army Medical Corps 2015
Leo J Schep R J Slaughter D I McBride

INTRODUCTION 2-Chloroacetophenone (CN), o-chlorobenzylidene malonitrile (CS) and oleoresin capsicum (OC) are common riot control agents. While serious systemic effects are uncommon, exposure to high concentrations may lead to severe complications and even death. The aim of this narrative review is to summarise all main aspects of the riot control agents CN, CS and OC toxicology, including mecha...

Journal: :iranian journal of public health 0
yu bin ho mohamad pauzi zakaria puziah abdul latif nazamid saari

background: repeated applications of animal manure as fertilizer are normal agricultural practices in malaysia that may release veterinary antibiotics to environment from treated animals. methods: environmental risk assessment (era) on 5 commonly used antibiotics and one hormone in malaysian broiler farm was calculated using the ratio of measured environmental concentration (mec) and predicted ...

Abolghasemi, Shahla, Atashi, Hesam Adin , Niknegad, Mohammad Hadi , Zaferani Arani, Hamid,

Background: Tennis elbow (TE), as a lateral epicondylitis (LE), is a chronic inflammatory and degenerative tendon disease that causes pain in the outer part of the elbow. This study aimed to evaluate the efficacy of topical Trinitrate Glyceryl (GTN) in the treatment of patients with TE. Materials and methods: In this double-blind clinical trial, 90 patients with TE, referred to Orthopedic and R...

2015
Mathew Varkey Jie Ding Edward E. Tredget Francesco Puoci

Skin protects the body from exogenous substances and functions as a barrier to fluid loss and trauma. The skin comprises of epidermal, dermal and hypodermal layers, which mainly contain keratinocytes, fibroblasts and adipocytes, respectively, typically embedded on extracellular matrix made up of glycosaminoglycans and fibrous proteins. When the integrity of skin is compromised due to injury as ...

2011
Rajendran Sellamuthu Christina Umbright Rebecca Chapman Stephen Leonard Shengqiao Li Michael Kashon Pius Joseph

1Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV 2Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV 3Biostatistics and Epidemiology Branch, Health Effects Laboratory Division, National...

2014
Abhishek Adhya Jayanta Bain Oindri Ray Avijit Hazra Souvik Adhikari Gouranga Dutta Sudhin Ray Bijay Kumar Majumdar

BACKGROUND Silver sulfadiazine (SSD) has been the standard topical antimicrobial for burn wounds for decades. Recently, nanometer-sized silver particles are available which have high surface to volume ratio and remain effective even at a very low concentration and minimizes the chance for tissue toxicity due to silver. Hence, we conducted a randomized controlled trial to compare the effectivene...

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