background and aims: p504s (amacr) is a mitochondrial enzyme expressed in renal cell carcinoma. some of immunohistochemical markers in renal cell tumors are independent prognostic factor and show relation with histologic grading. amacr expression increases with higher histological grading in different tumors; however, in rcc it is not obvious. in this study, we tried to investigate if any relat...

the paranasal sinuses are known to be a rare location for metastasis. renal cell carcinoma (rcc) is the most frequent primary tumor to metastasize to the sinonasal region, followed by lung and breast cancer. in particular, clear cell type rcc, which represents approximately 85% of rccs, is characterized by early metastasis, and it sometimes spreads to unusual sites (1, 2). metastatic tumors in ...

To evaluate the clinicopathologic features of renal cell carcinoma in younger adults (</=40 years), we retrospectively reviewed 838 consecutive cases of renal cell carcinoma (RCC) occurred in a single tertiary hospital. Forty-four 44 (5.2%) cases occurred in the young adult group (24 to 40 years of age). Clinicopathologic features including tumor size, stage, histologic subtype, lymph node and ...

BACKGROUND To assess semiquantitative parameters of dynamic contrast-enhanced perfusion MR imaging (DCE) in differentiation of subtypes of renal cell carcinoma (RCC). MATERIAL/METHODS Prospective study conducted upon 34 patients (27 M, 7 F, aged 25-72 ys: mean 45 ys) with RCC. Abdominal dynamic contrast-enhanced gradient-recalled echo MR sequence after administration of gadopentetate dimeglum...

Renal cell carcinoma (RCC) constitutes an array of morphologically and genetically distinct tumors the most prevalent of which are clear cell, papillary, and chromophobe RCC. Accurate distinction between the typically benign-behaving renal oncocytoma and RCC subtypes is a frequent challenge for pathologists. This is critical for clinical decision making. Subtypes also have different survival ou...

Renal oncocytoma is considered to be a benign tumor that shares some phenotypic features with chromophobe renal cell carcinoma (RCC). Recently, we described high frequencies of allelic loss at 1p, 2p, 6p, 10p, 13q, 14q, 17p, and 21q, which correlate significantly with the chromophobe subtype of RCC. To investigate the genetic relationship between these two entities, we examined 12 oncocytomas f...

BACKGROUND Adult renal epithelial neoplasms are a heterogeneous group with varying prognosis and outcome requiring sub-classification. METHODS Cases of renal cell carcinoma (RCC) in a 10 years period were analyzed with regard to the clinical features and histology. Sections were reviewed by four pathologists and the discordant cases were resolved with the help of Hale's colloidal iron stain, ...