Background: Acute syphilitic posterior placoid chorioretinopathy (ASPPC) is a rare but defining characteristic of ocular syphilis. Clinical findings are subtle, geographic, yellowish, macular lesions, affecting the outer-retina and inner choroid, often associated with subretinal fluid in early phase. This case report will review clinical signs ASPPC to aid practitioner identification recognitio...

The diagnosis of necrotising viral chorioretinitis in a child with leukaemia in remission was confirmed by the presence of viral particles on electron microscopy. Biopsy from the blind eye differentiated between leukaemic infiltrates and an infectious process after further investigations initially failed to support either diagnosis. Diagnostic chorioretinal biopsy may be indicated in a blind ey...

By using a modified enzyme immunoassay we have conducted a detailed study on the intraocular synthesis of toxoplasma antibodies during ocular toxoplasmosis. In control patients operated on for cataracts, the ratio of immunoglobulin G (IgG) toxoplasma antibodies in serum to those in aqueous humor was more than 100. In eight of the nine patients with clinically diagnosed toxoplasmic chorioretinit...

A difficult case 289 Hypoactive–hypoalert behaviour and thalamic hypometabolism due to intracranial hypotension S Kearney, P Flynn, S Hughes, W Spence, M O McCarron 293 Chorioretinitis: a potential clue to the early diagnosis of subacute sclerosing panencephalitis V Jeevagan, A Dissanayake 297 Acute segmental poliomyelitis-like flaccid paralysis in an adult in the UK, associated with enteroviru...

Candida endophthalmitis represents the most serious ocular complication of candidemia. The pharmacokinetics and pharmacodynamics of fluconazole, amphotericin B, and flucytosine are fairly well established in endophthalmitis therapy. There remains a paucity of clinical data regarding the utility of new antimycotic agents in the treatment of fungal chorioretinitis and endophthalmitis. We report a...

Purpose The purpose of this study was to describe fundus autofluorescence (FAF) findings in eyes with birdshot chorioretinitis (BSCR) and to compare findings to demographic, medical, and clinical characteristics. Methods In this multicenter, prospective, cross-sectional study, 172 eyes (86 patients) with BSCR were investigated. Participants underwent a standardized evaluation including collec...

The patient was in his usual state of excellent health preceding the episode. He reported mild pressure in the affected eye along with a constant, bilateral, temporal headache that may have predated the blurred vision. The headache was readily relieved by acetaminophen. He denied flashes, photosensitivity, or other visual aberrations. He maintained that his vision was “weaker” on the right at b...