PURPOSE To identify the causative paired box 6 (PAX6) mutation in a family with autosomal dominant aniridia. METHODS A family with autosomal dominant aniridia with three affected individuals in two generations was investigated for the causative PAX6 mutation by single strand conformation polymorphism (SSCP) followed by sequencing of genomic DNA from peripheral blood. RESULTS A novel PAX6 mu...

Microphthalmos occupies a spectrum from a normal, but small globe, to a globe with multiple anterior and posterior segment abnormalities. This study examines 54 eyes of 27 patients who had bilateral microphthalmos and severe visual impairment or blindness. Congenital cataract was the commonest cause of severe visual impairment (44%), followed by presumed retinal or optic nerve dysplasia (30%) a...

OBJECTIVE To perform fluorescein and indocyanine green angiography for large or peripheral chorioretinal structures using a contact lens system that provides a 5-fold increase in the field of view of a confocal scanning laser ophthalmoscope (SLO). METHODS Separate handheld contact and noncontact ophthalmoscopic lenses were manually aligned with the optical axis of a confocal SLO to demonstrat...

 In this paper, we aresupposed to introduce the definitions of n-fold commutative, andimplicative hyper K-ideals. These definitions are thegeneralizations of the definitions of commutative, andimplicative hyper K-ideals, respectively, which have been definedin [12]. Then we obtain some related results. In particular wedetermine the relationships between n-fold implicative hyperK-ideal and n-fol...

purpose: to report a case who had optic disc duplication, a rare congenital disorder characterized by two well-defined discs in one eye. case report: a 19 months-old child presented with unilateral epiphora in the right eye since birthday. the right eye was smaller than the left eye and mild ptosis was apparent. nasolacrimal duct probing was performed under general anesthesia. the examination r...

purpose: to report a case of hypotonous maculopathy after blunt trauma and its treatment. patient and findings: a 34-year-old woman presented with decreased visual acuity in her left eye following blunt trauma. right eye examination was unremarkable, but visual acuity of left eye was counting fingers. slit lamp biomicroscopy of the left eye was within normal limits, but on funduscopy, papilloma...