BACKGROUND Chlorhexidine is used for disinfection of skin and mucosae in medicine and dentistry. Prolonged exposure may lead to contact sensitization and allergic contact dermatitis or stomatitis. OBJECTIVES The purpose of this study was to analyse the sources of chlorhexidine exposure and sensitization, and to obtain data on the prevalence of sensitization and chlorhexidine-related contact a...

INTRODUCTION The aim of this in vitro study was to evaluate the antimicrobial activity of four intracanal medicaments on Enterococcus Faecalis (E. Faecalis). METHODS AND MATERIALS Fifty extracted single-rooted human teeth were prepared with standard method. After contaminating the canals with E. Faecalis, the samples were divided into one control and four experimental groups (n=10). The teeth...

Introduction: The aim of the study was to evaluate the sustained release effect of 2% chlorhexidine and its combination with 2% chitosan, in vitro. Method: The sustained release effect of chlorhexidine and its combination with chitosan was determined using a UV spectrophotometer. Results: UV spectrophotometer analysis for the sustained release of chlorhexidine showed that almost 100% of chlorhe...

CONTEXT Antimicrobial efficacy of subgingival chlorhexidine (CHX) application using two different vehicles of delivery. AIMS The aim was to evaluate the efficacy of CHX varnish and gel as an adjunct to scaling and root planing (SRP) in reducing microbial count within moderate to deep periodontal pockets. SETTINGS AND DESIGN Experimental parallel mouth study. SUBJECTS AND METHODS A total o...

BACKGROUND Skin antisepsis is a simple and effective measure to prevent infections. The efficacy of chlorhexidine is actively discussed in the literature on skin antisepsis. However, study outcomes due to chlorhexidine-alcohol combinations are often attributed to chlorhexidine alone. Thus, we sought to review the efficacy of chlorhexidine for skin antisepsis and the extent of a possible misinte...

BACKGROUND Chlorhexidine may cause type I and type IV allergy. Some chlorhexidine-allergic individuals have been exposed in the healthcare setting as patients or healthcare workers, but for others the source of sensitization is unknown. Chlorhexidine may be used as a preservative or an antimicrobial agent in cosmetic products at a concentration up to 0.3%, as set by the European Cosmetics Direc...

BACKGROUND Chlorhexidine gluconate is a widely used antimicrobial agent. Adding chlorhexidine and quaternary ammonium compounds to filling materials, such as composite resins, acrylic resins, and glass ionomer cements increases the antibacterial property of restorative materials. This study includes antibacterial property of glass ionomer restorative cements with chlorhexidine gluconate. AIM ...

Methods Observational analysis using ENVIN-HELICS database of all the infected and/or colonized patients in our ICU between January and May 2014 and to describe the multi-disciplinary measures performed for it ́s control: hygiene measures (strict hand hygiene, patients daily wash with special chlorhexidine gel, strict contact isolation), clustering measures (grouping all positive patients in ICU...

The recent COVID-19 pandemic provoked an outstanding increase of infection-control measures, with chlorhexidine becoming extensively used antiseptic. Allergic contact dermatitis to is considered as a rare event in children, often difficult identify, and its diagnosis misdiagnosed other skin diseases. We aimed explore the sensitization chlorhexidine-containing antiseptics infants children determ...