This article presents a method to investigate how magnetic particle characteristics affect their motion inside tissues under the influence of an applied magnetic field. Particles are placed on top of freshly excised tissue samples, a calibrated magnetic field is applied by a magnet underneath each tissue sample, and we image and quantify particle penetration depth by quantitative metrics to ass...

A magnetic nanocomposite film with the capability of reversibly collecting functionalized magnetic particles was fabricated by simultaneously imposing two orthogonal stimuli (electrical and magnetic). We demonstrate that cathodic codeposition of chitosan and Fe3O4 nanoparticles while simultaneously applying a magnetic field during codeposition can (i) organize structure, (ii) confer magnetic pr...

Magnetic iron oxide nanoparticles have gained a lot of attention in drug delivery systems because they can control a drug pathway to deliver it to the specific site under a magnetic field which is related to their magnetic core and surface coating. Chitosan-coated FeNPs, have prominent antimicrobial and biological properties that make chitosan a promising biopolymer for drug delivery applicatio...

Magnetic iron oxide nanoparticles have gained a lot of attention in drug delivery systems because they can control a drug pathway to deliver it to the specific site under a magnetic field which is related to their magnetic core and surface coating. Chitosan-coated FeNPs, have prominent antimicrobial and biological properties that make chitosan a promising biopolymer for drug delivery applicatio...

Biological materials offer a wide range of multifunctional and structural properties that are currently not achieved in synthetic materials. Herein we report on the synthesis and preparation of bioinspired organic/inorganic composites that mimic the key physicochemical features associated with the mechanical strengthening of both squid beaks and mussel thread coatings using chitosan as an initi...

polyvinylpyrrolidone (PVP) can markedly enhance the dissolution of poorly water-soluble drugs. The mechanism responsible for such enhanced dissolution has been the subject of debate. Some authors have proposed that the increased drug dissolution rate is due to the formation of a high-energy amorphous drug phase. Several water-soluble polymer carrier systems, such as polyethylene glycol (PEG), P...

background: influenza outbreak has become a great lifethreateningdisease in the world. nasal vaccines can inducesystemic igg and mucosal iga antibody responses, whichestablish two layers of immune defense against the infectiouspathogens like influenza. mucosal vaccines must overcomeseveral limitations, including the mucociliary clearance andinefficient uptake of soluble antigens. therefore, nas...

Introduction: Clinical application of platinum-based anticancer drugs is largely limited by severe toxicity. Drug delivery systems are highly desired for improving the efficacy and applicability of these drugs. This study describes an alternative strategy for the delivery of a new synthesized Pt(II) complex (bipyridin morpholin dithio carbomate Pt(II) nitrate) by its encapsulating in the Beta-C...

Curcumin is an herbal plant with great therapeutic applications. Although it is useful in treating several diseases, its low solubility in water and low bioavailability in living systems are limiting factors in using curcumin as a medicine. One way to overcome these shortcomings is the production of curcumin micro/nano particles. In this research, the particles of curcumin loaded with polycapro...