5-Fluorouracil (5-FU) is the backbone of the chemotherapy regimens approved for treatment of many malignancies, especially colorectal cancer (CRC). The incidence of cardiotoxicity associated with 5-FU ranges between 1.5% to 18% and is most commonly manifested as anginal symptoms. Cardiomyopathy is very rarely reported with 5-FU and capecitabine. A 35-year-old Caucasian male with T3, N1, M0 rect...

IntroductionIntramural Great Vessel lymphoma (IMGVL) is an extremely rare proliferating within the lumina of large vessels like Superior vena cava and Aorta. We present a case IMGVL presenting in patient with Left Ventricular Assist Device (LVAD).Case ReportA 63-year-old male ischemic cardiomyopathy advanced systolic failure supported by LVAD as bridge to transplant, presented clinic complainin...

the aim of the study was to evaluate the clinical usefulness of n-terminal pro-brain natriuretic peptide (nt-pro bnp) and nitric oxide (no) with echocardiography (gold standard test) in diagnosis of canine cardiomyopathy. out of 374 cases, 82 cases showing cardiovascular abnormalities including 16 cases of cardiomyopathy were further selected for standardization of biomarkers. significant (p

a 40 year old male, a known case of hypertrophic cardiomyopathy, was admitted for catheterization. at catheterization and angiography, septum was hypertrophied to about 5cm and diffuse coronary artery aneurysm was revealed. we found no previous report of coronary artery aneurysm in hypertrophic cardiomyopathy.

Along with a pronounced antitumor effect, Doxorubicin causes systemic effects damage to vital organs, including the heart. It prompts search for ways prevent cardiotoxic effect of drug, one which could be its intravesical administration. The aim study was develop method serial administration in medium therapeutic doses an experiment and evaluate drug. 42 female Wistar rats were included study. ...

conclusions according to our multimodality imaging approach, hypertrophic cardiomyopathy was the most probable diagnosis. case presentation we describe a 73-year-old woman referred to us for consultation because of a giant negative t wave on her electrocardiography. echocardiography revealed diffuse severe hypertrophy associated with hypertrophied anterolateral papillary muscles with a bifid he...

OBJECTIVES The purpose of this study was to estimate heart failure (HF) and cardiomyopathy (CM) rates after adjuvant trastuzumab therapy and chemotherapy in a population of older women with early-stage breast cancer. BACKGROUND Newer biologic therapies for breast cancer such as trastuzumab have been reported to increase HF and CM in clinical trials, especially in combination with anthracyclin...

A nthracyclines are potent antineoplastic agents with proven efficacy in the treatment of many pediatric and adult hematologic and solid organ cancers. Dose-dependent anthracycline-induced cardiomyopathy is the most notorious and well-studied chemotherapy-induced cardiovascular toxicity that was first described in 1971 in 67 patients treated with Adriamycin for a variety of tumors. 1 The clinic...