Comparing a solution phase route to a solid phase route in the synthesis of the cytotoxic natural product urukthapelstatin A (Ustat A) confirmed that a solid phase method is superior. The solution phase approach was tedious and involved cyclization of a ridged heterocyclic precursor, while solid phase allowed the rapid generation of a flexible linear peptide. Cyclization of the linear peptide w...

This paper studies the optimal placement of web files for en-route web caching. It is shown that existing placement policies are all solving restricted partial problems of the file placement problem, and therefore give only sub-optimal solutions. A dynamic programming algorithm of low complexity which computes the optimal solution is presented. It is shown both analytically and experimentally t...

Background: There is extensive variety of chemical compounds with antiulcer activity, which are isolated from medicinal plants. Matricaria chamomilla or Matricaria recutita or German chamomile, also spelled chamomile (MC), is one of the most widely used medicinal plants. In the present study, the extract of MC flowers was evaluated for antiulcerogenic activity and acute toxicity profile. Method...

In the present study, the capability of accumulative roll bonding (ARB) and subsequent heat-treatment to fabricate solid solution from a multilayered Cu/Zn/Al was investigated. Two post-heat treatment (one-step and two-step) routes were proposed. In the first, the ARB processed material was heated to 800 C for 5:30 hours and allowed to cool slowly in a furnace (one-step route). In the second (t...

The passenger line planning is a process of strategic long-term decision-making problem in the field of railway passenger planning. A line is a route between starting point and destination with certain stops, which has a certain frequency of train schedule. A new solution based on decomposition algorithm has been proposed in this paper, which is defined in a master problem and two sub problems....

The paper puts forward an unmanned aerial vehicle (UAV) fixed-point reconnaissance route planning method. The method introduces the improved particle swarm optimization (IPSO) method to the planning of UAV reconnaissance route and adds the objective value, effective reconnaissance route and other factors affecting UAV reconnaissance route in the objective function of particle swam to obtain the...

the present work deals with the synthesis and characterization of cds nanoparticles with good thermal stability and optical properties by a novel and simple synthetic route. the nanoparticles were synthesized via chemical precipitation method in a single reaction vessel under ambient conditions. the prepared cds nanoparticles were compared with the bulk cds. the optical properties were determin...