Over the last decades the inhibition of plasma cholinesterase (ChE) activity has been widely used as a biomarker to diagnose organophosphate and carbamate exposure. Plasma ChE activity is a useful and non-invasive method to monitor bird exposure to anticholinesterase compounds; nonetheless several studies had shown that the ChE form(s) present in avian plasma may vary greatly among species. In ...

We describe a stochastic simulation model that simulates avian foraging in an agricultural landscape to evaluate factors affecting dietary insecticide exposure and to predict post-exposure cholinesterase (ChE) inhibition. To evaluate the model, we simulated published field studies and found that model predictions of insecticide decay and ChE inhibition reasonably approximated most observed resu...

Living in complexity and being part of it, becoming self-aware, recognizing the other’s right to existence, embodying nature oneself as a natural, obvious everyday fact depends, Edgar Morin said, on our educational system. To do this, we need activate process that focuses direct experience with what surrounds us, particular nature, remembering education is kindling flame, not filling vessel.Sta...

La sfida raccolta da DULP richiede un approccio innovativo che consenta di riconsiderare le pratiche e l'idea di formazione, allo scopo di offrire supporto a forme di apprendimento che vanno assumendo un carattere temporale, spaziale e culturale sempre più ubiquo e che si svolgono in contesti sempre più liquidi e coevolutivi, in cui l'individuo deve necessariamente apprendere a gestire la propr...

The genes for acetylcholinesterase (ACHE) and butyrylcholinesterase (CHE) are expressed in multiple tumor tissues, including ovarian carcinomas. Both CHE and ACHE genes coamplify in leukemias. To examine the relationship of gene amplification to the expression of these genes in tumors, ACHE and CHE genes and their expression were studied in primary ovarian carcinomas. DNA blot hybridization dem...

Riassunto: Il Bagging è una tecnica di aggregazione, in cui uno stimatore viene ottenuto come media di predittori calcolati su campioni bootstrap. Gli alberi di decisione con il bagging quasi sempre migliorano il predittore originario, ed è opinione comune che l’efficacia del bagging sia dovuta alla riduzione della varianza. In questo lavoro mostriamo un contro-esempio e diamo evidenza sperimen...

Cholinesterase (ChE, EC 3.1.1.7) activity was investigated in gills and adductor muscle of two bivalve species: Arca noae and Venus verrucosa. The properties of ChEs were investigated using acetylcholine iodide (ASCh), butyrylcholine iodide (BSCh) and propionylcholine iodide (PrSCh) as substrates and eserine, BW254c51 and iso-OMPA as specific inhibitors. The highest level of ChE activity in cru...

BACKGROUND The prevalence and economic burden of chronic diseases are increasing worldwide. Nevertheless, little information is available on catastrophic health expenditures (CHE) associated with chronic diseases in Korea. This study explored the burden of household out-of-pocket health expenditures among the Korean population for different chronic diseases. METHODS This study was conducted u...