AIMS Continuous glucose monitoring (CGM) using transcutaneous sensors is becoming a sophisticated method to control and regulate glucose metabolism. The transcutaneous sensor of the CGM system (CGMS Medtronic Minimed, Northridge, CA, USA) is chosen to measure glucose concentration in interstitial fluid up to three days after insertion even though its function remains stable for a longer period....

Parameters of glucose dynamics recorded by the continuous glucose monitoring system (CGMS) could help in the control of glycemic fluctuations, which is important in diabetes management. Multiscale entropy (MSE) analysis has recently been developed to measure the complexity of physical and physiological time sequences. A reduced MSE complexity index indicates the increased repetition patterns of...

BACKGROUND Impaired glucose metabolism plays an important role in patients with acute myocardial infarction, but the clinical significance of glycemic variability (GV) early after the onset of ST-segment elevation myocardial infarction (STEMI) remains to be fully elucidated. METHODS AND RESULTS We prospectively investigated the clinical impact of GV, as determined by a continuous glucose moni...

PURPOSE Diabetes mellitus (DM) is the most common cause of end-stage renal disease and is an important risk factor for morbidity and mortality after dialysis. However, glycemic control among such patients is difficult to assess. The present study examined glycemic control parameters and observed glucose variation after refilling different kinds of fresh dialysate in peritoneal dialysis (PD) pat...

OBJECTIVE Safety of fasting in Ramadan for diabetic patients is not clearly known. The aim of this study was to determine the effects of fasting on glycemic excursions by continuous glucose monitoring system (CGMS). MATERIALS AND METHODS This pilot, observational study conducted in the Endocrine Research Center, Mashhad University of Medical Sciences, Mashhad, IRAN, in Ramadan 2008. Seventeen...

We are interested in supporting software evolution caused by changing requirements and/or changes in the operational environment of a software system. For example, users of a system may want new functionality or performance enhancements to cope with growing user population (changing requirements). Alternatively, vendors of a system may want to minimize costs in implementing requirements changes...

We are interested in supporting software evolution caused by changing requirements and/or changes in the operational environment of a software system. For example, users of a system may want new functionality or performance enhancements to cope with growing user population (changing requirements). Alternatively, vendors of a system may want to minimize costs in implementing requirements changes...

UNLABELLED Patients with nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) often have metabolic disorders including insulin resistance and type 2 diabetes mellitus (T2DM). We clarified the predictive factors in glucose metabolism for progression of hepatic fibrosis in patients with NAFLD by the 75-g oral glucose tolerance test (75gOGTT) and a continuous glucose mo...

BACKGROUND Although rapid progression (RP) of coronary artery disease (CAD) has been shown to be a powerful predictor of cardiovascular events, predictors of RP are not fully understood in patients with acute coronary syndrome (ACS). METHODSANDRESULTS We prospectively investigated the clinical impact of glycemic variability (GV), as determined on continuous glucose monitoring system (CGMS), o...

BACKGROUND The objective of this article was to focus on the application of harmonic decomposition to continuous glucose monitor (CGM) measurements. We show evidence of an attenuation of fast variations of interstitial glucose when compared to blood in type 1 diabetes mellitus (T1DM) and, using information theory, propose optimal sampling schedules associated with the use and study of CGMs. M...