Capping agents, key for nanoparticle stability, may hugely influence chemical behaviour. We show that differently capped gold nanoparticles, with either citrate or cetyl trimethylammonium bromide (CTAB) capping agents, show qualitatively different electron transfer properties. Specifically through cyclic voltammetry and nanoimpact studies the CTAB promoted dissolution of gold nanoparticles is s...

In this work, the effect of cellulosic polymer and chemical structure of salicylic acid and its various esters on their release has been analysed. The release of different drugs in distinct types of vehicles, cetyl excipient, polyethylene glycol and Carbopol gel was also studied.  2001 Published by Elsevier Science B.V.

Quaternary ammonium compounds (QACS) are employed both as disinfectants for manual processing lines and surfaces in the food industry, and in human medicine area. QACS also cause cell death by protein denaturation . One of the QAC is cetyl trimethyl ammonium bromide (CTAB) that appears to rapture the cell membrane. The primary site of action of CTAB has been suggested to be the lipid components...

Ibuprofen is one of the most important non-steroidal anti-inflammatory drugs used in the treatment of inflammatory diseases. In its pure state, ibuprofen presents poor physical and mechanical characteristics and its use in solid dosage forms needs the addition of excipients that improve these properties. The selection of the best excipients and the most suitable pharmaceutical dosage form to ca...

Sustained release matrix pellets of the freely water soluble drug, betahistine dihydrochloride (BH), were prepared using freeze pelletization technique. Different waxes and lipids (cetyl alcohol, beeswax, glyceryl tripalmitate (GTP) and glyceryl tristearate) were evaluated for the preparation of matrix pellets. A D-optimal design was employed for the optimization and to explore the effect of dr...

Objective: The aim of this study to manufacture the prolonged release lipid nanoparticle (Solid and nanostructure carrier) repaglinide for enhance oral bioavailability. Methods: Solid nanoparticles (SLN) Nanostructured carriers (NLC) were prepared by slight modification in solvent diffusion method. core material used as cetyl alcohol while blend with oleic acid was preparation NLC dispersion. T...

Decapeptide KSL-W shows antibacterial activities and can be used in the oral cavity, however, it is easily degraded in aqueous solution and eliminated. Therefore, we aimed to develop liquid crystalline systems (F1 and F2) for KSL-W buccal administration to treat multispecies oral biofilms. The systems were prepared with oleic acid, polyoxypropylene (5) polyoxyethylene (20) cetyl alcohol (PPG-5-...

Spontaneous formation of ruthenium nanochains is accomplished in aqueous medium under mild conditions using a seed mediated protocol with cetyl trimethylammonium bromide (CTAB) as the capping agent. They are formed due to the random self-assembly of Ru seeds of ∼3.5 nm size. These 1D nanostructures exhibit better catalytic activity towards the oxidation of CO relative to the ∼3.5 nm seeds and 6...

Hydrophilic polymers alone are not quite efficient in controlling the release of highly water soluble drugs. Hydrophobic Polymer and pore forming agent have been extensively investigated for sustaining the release of drug. They provide several advantages include good stability at varying pH ranges and effectively retards the water soluble drug. In the present study it was a novel approach where...