Name of Sponsor /Company: Individual Study (For National L7CB S.A. Pharma Sector Table Referring to Authority Use Part IV Only) Of the Dossier Name of Finished Product: Volume: Zyrtec@ Name of Active Ingredient: Page : Cetirizine dihydrochloride Title of Study: EARLY TREATMENT OF THE ~TOPIC ~HILD (E.T.A.C.@) EVALUA=ION OF THE EFFICACY AND SAFETY OF CETIRIZINE IN PREVENTING THE ONSET OF ASTHMA I...

BACKGROUND The association between genetic predisposition and environmental risk factors such as passive smoke in determining respiratory allergies is still uncertain; even less is known about the role played by passive smoking in influencing the success of therapy for rhinitis and allergic asthma. OBJECTIVE The purpose of this prospective, randomised study was to determine whether passive sm...

Several antihistaminics possess antibacterial activity against a broad spectrum of bacteria. However, the exact mechanism of such activity was unclear. Hence, the aim of this study is to investigate their mechanism of antibacterial activity especially their effect upon the permeability of the bacterial cytoplasmic membrane. The effects of azelastine, cetirizine, cyproheptadine and diphenhydrami...

The aim of the present study was to establish antihistamines drug prescribing pattern in order to improve the rational prescribing of antihistamines by physicians at Panjab University Health Centre. The study was performed in between the months of November 2005 to April 2006. Five hundred out patients were monitored and data was collected on WHO-based prescription-auditing performa. Demographic...

The tuberomammillary nucleus (TMN) of the posterior hypothalamus has a high density of histaminergic neurons, the projection fibers of which are present in many areas of the brain, including the nucleus tractus solitarius (NTS), which controls arterial pressure (AP). In this study, we investigated whether the TMN-NTS pathway is involved in central cardiovascular regulation. Bicuculline, a gamma...