Cerebral vein thrombosis, also called superior sagittal sinus thrombosis, is a well recognized clinical and radiologic entity associated with a variety of medical disorders. We report a patient with fatal cerebral vein thrombosis following myelography, in whom the cause was familial antithrombin III (AT3) deficiency. Unsuspected AT3 deficiency should be considered in cases of unexplained cerebr...

Cerebral venous thrombosis is a potentially lethal disease. Early diagnosis is essential to improve its prognosis. However, its early diagnosis based on conventional imaging modalities remains a challenge in clinical settings. The purpose of this study was to evaluate whether bright sinus appearance on arterial spin-labeling perfusion-weighted image (ASL-PWI) could help identify cerebral venous...

BACKGROUND Although Sjögren's syndrome has been known to complicate with white matter lesions, encephalopathy, or stroke, reports of cerebral venous sinus thrombosis due to Sjögren's syndrome with atypical antibodies are rare. CASE REPORT A 50-year-old woman was admitted to our neurological ward with nausea and vomiting following acute onset of severe headache in the left occipital region. Br...

A cerebral venous malformation ruptured after acute thrombosis of its central draining venous channel, leading to intracerebral hemorrhage. The CT, MR, and angiographic studies unequivocally demonstrated subsequent progressive recanalization of the malformation, providing proof that venous malformations can spontaneously bleed and that venous thrombosis may be associated with, and perhaps produ...

BACKGROUND Cerebral venous thrombosis is a rare complication of polycythemia. To our knowledge, epoetin alfa-induced polycythemia has not previously been reported in association with cerebral venous thrombosis. CASE DESCRIPTION A 37-year-old patient who was receiving peritoneal dialysis and epoetin alfa (Epogen) therapy presented with a several-day history of worsening headache, and a neuroim...

Venous thrombosis is associated with Virchow’s triad. This involves the combination of hypercoagulability, damage to the vessel endothelium and haemodynamic changes in the form of stasis or turbulence. These features ultimately contribute to thrombosis formation (Heit 2008). Venous thrombosis can affect the eyes, resulting in serious ocular symptoms and is a significant cause of vision loss wor...

Evidence-Basis for Anticoagulants for Cerebral Sinus Venous Thrombosis? To the Editor: The recent case of cerebral sinus venous thrombosis (CSVT) in the US Secretary of State Hillary Clinton brought my attention to articles that lay out the evidence-basis for the use of full dose heparin and oral anticoagulant drugs for CSVT. Unfortunately, articles published in Stroke by investigators from the...

Venous thrombosis typically involves the lower extremity circulation. Rarely, it can occur in the cerebral or splanchnic veins and these are the most frightening manifestations because of their high mortality rate. A third site of rare venous thrombosis is the deep system of the upper extremities that, as for the lower extremity, can be complicated by pulmonary embolism and post-thrombotic synd...

Sinovac is an inactivated virus COVID 19 vaccine given emergency authorization for Pandemic. Different adverse reactions have been seen in after marketing of vaccines. Here we present a case patient who developed cerebral venous sinus thrombosis two weeks the first dose SINOVAC vaccine.

Background: Cerebral venous sinus thrombosis (sinovenous) (CSVT) is a rare and yet an important cause of morbidity and mortality in neonates. The Canadian registry quotes an incidence of 41 per 100,000 newborns per year. Cerebral sinovenous thrombosis is rarely reported in preterm infants. Although it is a potentially devastating condition with poor neuro developmental outcome, the risk factors...